{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T19:03:10Z","timestamp":1783191790598,"version":"3.54.6"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Gitelman syndrome (GS) is an autosomal recessive salt\u2010losing tubulopathy characterized by hypokalemia, hypomagnesemia, and metabolic alkalosis. Although often considered benign, GS may predispose to malignant ventricular arrhythmias.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>\n                      A 41\u2010year\u2010old male presented with cardiac arrest due to ventricular fibrillation (VF). Severe hypokalemia (1.6 mmol\/L) and hypomagnesemia were identified, with no structural heart disease on imaging. Recurrent VF persisted despite antiarrhythmic therapy and resolved only after electrolyte correction. Genetic testing revealed pathogenic\u00a0\n                      <jats:italic>SLC12A3<\/jats:italic>\n                      \u00a0variants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>GS can cause an electrical storm in structurally normal hearts; prompt recognition and electrolyte management are essential.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70302","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T16:29:52Z","timestamp":1779812992000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Compound Heterozygous\n                    <i>SLC12A3<\/i>\n                    Variants in Gitelman Syndrome Presenting With Ventricular Fibrillation and Cardiac Arrest"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9616-3386","authenticated-orcid":false,"given":"Hatice","family":"Kemal","sequence":"first","affiliation":[{"name":"Department of Cardiology Near East University Hospital  Nicosia Cyprus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9593-9325","authenticated-orcid":false,"given":"Mahmut Cerkez","family":"Ergoren","sequence":"additional","affiliation":[{"name":"Medical Genetics Diagnostic Laboratory Near East University Hospital  Nicosia Cyprus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Behich","family":"Koyutourk","sequence":"additional","affiliation":[{"name":"Medical Genetics Diagnostic Laboratory Near East University Hospital  Nicosia Cyprus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levent","family":"Cerit","sequence":"additional","affiliation":[{"name":"Department of Cardiology Near East University Hospital  Nicosia Cyprus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamza","family":"Duygu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Near East University Hospital  Nicosia Cyprus"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2016.09.046"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882\u2010020\u201001996\u20102"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2025.09.006"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.4022\/jafib.229"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2024.11.012"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr\u20102019\u2010232086"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.44464"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.5414\/cnp67193"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc051040"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.68.509"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2023.1188098"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523\u20101755.2002.00467.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh204"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.70302","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pace.70302","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.70302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T10:04:09Z","timestamp":1780653849000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.70302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,26]]},"references-count":13,"alternative-id":["10.1111\/pace.70302"],"URL":"https:\/\/doi.org\/10.1111\/pace.70302","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,26]]},"assertion":[{"value":"2026-04-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"pace.70302"}}