{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:02:27Z","timestamp":1789621347779,"version":"build-2803163510"},"reference-count":14,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Optimization of biventricular pacing for cardiac resynchronization therapy (CRT) with fusion (fusion\u2010optimized intervals method) has been shown to improve left ventricular remodeling. However, information on programming the atrioventricular (AV) interval during left bundle branch pacing (LBBP) is scarce.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Assess with electrocardiographic imaging (ECGI) the electrical benefit of optimization of the AV interval during LBBP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective analysis of prospectively collected data. Pilot study including patients who received LBBP with CRT indication, normal AV conduction, sinus rhythm, and left bundle branch block. ECGI was used to obtain non\u2010invasive activation maps, ventricular activation times, and QRS widths during the optimization of the AV interval.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 10 patients who received LBBP were included. Median age was 62 years (57\u201374 years), 40% were women, 20% had ischemic cardiomyopathy, and baseline LVEF was 29% (23%\u201336%). The baseline median QRS duration was 178\u00a0ms (168\u2013187\u00a0ms), with a left ventricular activation time (LVAT) of 99\u00a0ms (90\u2013109\u00a0ms), a right ventricular activation time (RVAT) of 42\u00a0ms (34\u201371\u00a0ms), and a total ventricular activation time (TAT) of 111\u00a0ms (105\u2013131\u00a0ms).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>A non\u2010tailored AV programming showed a QRS measured from intrinsic deflection of 142\u00a0ms (137\u2013149\u00a0ms); when a tailored AV was programmed, the median QRS decreased to 124\u00a0ms (116\u2013130\u00a0ms). Ventricular activation times showed shortening with a tailored approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>AV interval adjustment during left bundle branch pacing may result in better resynchronization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70413","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T04:15:32Z","timestamp":1789618532000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Tailoring the Atrioventricular Interval During Left Bundle Branch Pacing: Playing With Fusion"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4523-6469","authenticated-orcid":false,"given":"Margarida","family":"Pujol\u2010Lopez","sequence":"first","affiliation":[{"name":"Institut Cl\u00ednic Cardiovascular (ICCV) Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS) Barcelona Catalonia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6864-9372","authenticated-orcid":false,"given":"Mariona","family":"Regany\u2010Closa","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic Cardiovascular (ICCV) Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS) Barcelona Catalonia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4238-5319","authenticated-orcid":false,"given":"Eduard","family":"Guasch","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic Cardiovascular (ICCV) Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS) Barcelona Catalonia Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red; Enfermedades Cardiovasculares (CIBERCV) Instituto de Salud Carlos III Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paz","family":"Garre","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic Cardiovascular (ICCV) Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS) Barcelona Catalonia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2613-2920","authenticated-orcid":false,"given":"Mireia","family":"Niebla","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic Cardiovascular (ICCV) Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS) Barcelona Catalonia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4980-5544","authenticated-orcid":false,"given":"Esther","family":"Carro","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic Cardiovascular (ICCV) Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS) Barcelona Catalonia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3270-0733","authenticated-orcid":false,"given":"Rebeca","family":"Domingo","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic Cardiovascular (ICCV) Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS) Barcelona Catalonia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2752-5264","authenticated-orcid":false,"given":"Ivo","family":"Roca\u2010Luque","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic Cardiovascular (ICCV) Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS) Barcelona Catalonia Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red; 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