{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T04:07:47Z","timestamp":1788754067989,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T00:00:00Z","timestamp":1788652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T00:00:00Z","timestamp":1788652800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"abstract":"ABSTRACT<\/jats:title>\n \n Introduction<\/jats:title>\n Patient characteristics and predictors of early (ERAT) and late (LRAT) recurrence of atrial tachyarrhythmia by atrial fibrillation (AF) type after cryoballoon ablation (CBA) remain poorly defined.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Using the Korean Heart Rhythm Cryoballoon Registry (12 centers, 2018\u20132022), 2051 patients undergoing CBA for drug\u2010refractory AF were stratified by AF type. ERAT was defined as atrial tachyarrhythmia within the 3\u2010month blanking period and LRAT as recurrence beyond 3 months. Independent predictors of ERAT (all patients) and LRAT (patients without ERAT) were identified.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n ERAT occurred in 631 patients (30.8%; 17.6% in paroxysmal and 40.4% in persistent AF). Among 1420 patients without ERAT, LRAT occurred in 311 (21.9%; 16.7% paroxysmal, 27.2% persistent). In paroxysmal AF, coronary artery disease (HR 1.60; 95% CI, 1.00\u20132.56;\n p<\/jats:italic>\n = 0.048) and LA enlargement (HR 1.07; 95% CI, 1.04\u20131.10;\n p<\/jats:italic>\n < 0.001) predicted ERAT, whereas hypertrophic cardiomyopathy (HR 5.01; 95% CI, 2.20\u201311.42;\n p<\/jats:italic>\n < 0.001) and LA enlargement (HR 1.04; 95% CI, 1.01\u20131.08;\n p<\/jats:italic>\n = 0.019) predicted LRAT. In persistent AF, AF duration (HR 1.04; 95% CI, 1.02\u20131.06;\n p<\/jats:italic>\n < 0.001) and LA enlargement (HR 1.03; 95% CI, 1.02\u20131.04;\n p<\/jats:italic>\n < 0.001) predicted ERAT, and LA enlargement (HR 1.03; 95% CI, 1.01\u20131.05;\n p<\/jats:italic>\n = 0.010) independently predicted LRAT.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Predictors of ERAT and LRAT differed between patients with paroxysmal and those with persistent AF. LA enlargement was the most consistently shared predictor across recurrence phenotypes.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/pace.70420","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T03:21:22Z","timestamp":1788751282000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictors of Early Versus Late Atrial Tachyarrhythmia Recurrence After Cryoballoon Ablation by Atrial Fibrillation Type"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8831-8344","authenticated-orcid":false,"given":"Jinsun","family":"Park","sequence":"first","affiliation":[{"name":"Division of Cardiology, Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea"},{"name":"Department of Internal Medicine, Division of Cardiology Hanyang University Medical Center, Hanyang University College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6180-0157","authenticated-orcid":false,"given":"Myung\u2010Jin","family":"Cha","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea"},{"name":"Cardiovascular Research Department Seoul Prime Heart Clinic Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8716-1146","authenticated-orcid":false,"given":"Chang Hee","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology Konkuk University Medical Center, Konkuk University School of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Soo","family":"Cho","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4391-5406","authenticated-orcid":false,"given":"Gi\u2010Byoung","family":"Nam","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Asan Medical Center University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Il\u2010Young","family":"Oh","sequence":"additional","affiliation":[{"name":"Cardiovascular Center Seoul National University Bundang Hospital, Seoul National University College of Medicine Seongnam Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6351-5015","authenticated-orcid":false,"given":"So\u2010Ryoung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University Hospital, Seoul National University College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2452-4423","authenticated-orcid":false,"given":"Ju Youn","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology, Heart Vascular Stroke Institute Samsung Medical Center, Sungkyunkwan University School of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1018-7871","authenticated-orcid":false,"given":"Sung Ho","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junbeom","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Cardiology, College of Medicine Ewha Womans University Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki\u2010Hun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Haeundae Paik Hospital Inje University College of Medicine Busan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6552-1742","authenticated-orcid":false,"given":"Pil\u2010Sung","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology Yongin Severance Hospital, Yonsei University College of Medicine Yongin Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Hyung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chungnam National University Hospital, Chungnam National University College of Medicine Daejeon Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8251-1522","authenticated-orcid":false,"given":"Jaemin","family":"Shim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology Korea University College of Medicine and Korea University Anam Hospital Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8102-8352","authenticated-orcid":false,"given":"Hong Euy","family":"Lim","sequence":"additional","affiliation":[{"name":"Division of Cardiology Chung\u2010Ang University Gwangmyeong Hospital, Chung\u2010Ang University College of Medicine Gwangmyeong Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,6]]},"reference":[{"issue":"23","key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1056\/NEJMoa1602014","article-title":"Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation","volume":"374","author":"Kuck K.\u2010H.","year":"2016","journal-title":"New England Journal of Medicine"},{"issue":"4","key":"e_1_2_11_3_1","doi-asserted-by":"crossref","DOI":"10.1093\/europace\/euae043","article-title":"2024 European Heart Rhythm Association\/Heart Rhythm Society\/Asia Pacific Heart Rhythm Society\/Latin American Heart Rhythm Society Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation","volume":"26","author":"Tzeis 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S.","year":"2020","journal-title":"Journal of Interventional Cardiac Electrophysiology"},{"issue":"3","key":"e_1_2_11_12_1","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/jce.15337","article-title":"Early Arrhythmia Recurrence After Cryoballoon Ablation in Atrial Fibrillation: A Systematic Review and Meta\u2010Analysis","volume":"33","author":"Vrachatis D. 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C.","year":"2024","journal-title":"European Heart Journal"},{"issue":"1","key":"e_1_2_11_18_1","first-page":"218","article-title":"Catheter Cryoablation: Biology and Clinical Uses","volume":"6","author":"Andrade J. G.","year":"2013","journal-title":"Circulation: Arrhythmia and Electrophysiology"},{"issue":"25","key":"e_1_2_11_19_1","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.1016\/j.jacc.2020.04.065","article-title":"Recurrence of Atrial Fibrillation After Catheter Ablation or Antiarrhythmic Drug Therapy in the CABANA Trial","volume":"75","author":"Poole J. E.","year":"2020","journal-title":"Journal of the American College of Cardiology"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.70420","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pace.70420","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.70420","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T03:21:27Z","timestamp":1788751287000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.70420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,6]]},"references-count":18,"alternative-id":["10.1111\/pace.70420"],"URL":"https:\/\/doi.org\/10.1111\/pace.70420","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,6]]},"assertion":[{"value":"2026-07-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"pace.70420"}}