{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T03:55:50Z","timestamp":1790826950329,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Same\u2010day discharge after cardiac implantable electronic device generator replacement may reduce hospital resource use, but evidence regarding its safety and patient acceptability remains limited. We evaluated the feasibility, safety, and patient\u2010reported acceptability of a day\u2010surgery pathway for isolated generator replacement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a multicenter retrospective observational study of consecutive adults undergoing isolated cardiac implantable electronic device generator replacement between February 2017 and October 2024. Procedures requiring lead revision, upgrade, extraction, or repositioning were excluded. Patients were managed either through a day\u2010surgery pathway with same\u2010day discharge or through an ordinary\u2010setting pathway. The primary endpoint was device\u2010related infection within 365 days. Secondary outcomes included pocket hematoma, patient preference, and recalled preprocedural anxiety assessed using the Amsterdam Preoperative Anxiety and Information Scale (APAIS) and the Anaesthesia and Surgery\u2010dependent Preoperative Anxiety (ASPA) scale, administered during follow\u2010up after the procedure. A hypothetical projection of bed\u2010day cost savings was also performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 416 procedures were analyzed: 216 in the day\u2010surgery group and 200 in the ordinary\u2010setting group. Within 365 days, device\u2010related infection occurred in 4 patients in the day\u2010surgery group and 5 in the ordinary\u2010setting group (1.9%\u00a0vs. 2.5%;\n                      <jats:italic>p =<\/jats:italic>\n                      0.743). One pocket hematoma occurred in the day\u2010surgery group and was managed conservatively without subsequent infection. Preference for day surgery was reported by 93.8% of evaluable patients in the day\u2010surgery group and 76.0% in the ordinary\u2010setting group (p &lt; 0.001). Recalled preprocedural APAIS and ASPA scores were significantly lower in the day\u2010surgery group. Using published Italian hospital micro\u2010costing data as an illustrative benchmark, the 216 day\u2010surgery procedures corresponded to a hypothetical reduction in hospital resource consumption of approximately \u20ac159,808.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Same\u2010day discharge after isolated generator replacement was feasible and well accepted and was not associated with a detectable increase in device\u2010related infection within 365 days. Recalled preprocedural anxiety scores were lower among patients managed through the day\u2010surgery pathway, although these assessments were obtained retrospectively during follow\u2010up. Same\u2010day discharge may represent a resource\u2010saving organizational pathway for selected patients, but its economic impact requires assessment in a formal health\u2010economic analysis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70459","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T03:15:39Z","timestamp":1790824539000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Same\u2010Day Discharge After Cardiac Device Generator Replacement: Safety and Patient Acceptability"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6604-1756","authenticated-orcid":false,"given":"Luigi","family":"Cocchiara","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Advanced Biomedical Sciences Federico II University of Naples  Naples Italy"},{"name":"Cardiology, Heart Department Pineta Grande Hospital  Castelvolturno, Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1683-6986","authenticated-orcid":false,"given":"Benedetta","family":"Brescia","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Advanced Biomedical Sciences Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Vaccariello","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Dentistry University of Salerno  Salerno Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluigi","family":"Comparone","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Advanced Biomedical Sciences Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0101-4609","authenticated-orcid":false,"given":"Raffaele","family":"Mauriello","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Advanced Biomedical Sciences Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4616-9300","authenticated-orcid":false,"given":"Lucio","family":"Addeo","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Advanced Biomedical Sciences Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6906-1766","authenticated-orcid":false,"given":"Stefano","family":"Nardi","sequence":"additional","affiliation":[{"name":"Cardiology, Heart Department Pineta Grande Hospital  Castelvolturno, Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2677-9214","authenticated-orcid":false,"given":"Procolo","family":"Marchese","sequence":"additional","affiliation":[{"name":"EP Lab Cardiology Mazzoni Hospital  AST Ascoli Piceno Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Gennaro","sequence":"additional","affiliation":[{"name":"EP Lab Cardiology Mazzoni Hospital  AST Ascoli Piceno Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5256-6459","authenticated-orcid":false,"given":"Alfonso","family":"Varriale","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Advanced Biomedical Sciences Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0522-1061","authenticated-orcid":false,"given":"Luigi","family":"Argenziano","sequence":"additional","affiliation":[{"name":"Cardiology, Heart Department Pineta Grande Hospital  Castelvolturno, Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5928-1669","authenticated-orcid":false,"given":"Teresa","family":"Strisciuglio","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Advanced Biomedical Sciences Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0565-7127","authenticated-orcid":false,"given":"Giovanni","family":"Esposito","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Advanced Biomedical Sciences Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4739-7004","authenticated-orcid":false,"given":"Antonio","family":"Rapacciuolo","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Advanced Biomedical Sciences Federico II University of Naples  Naples Italy"},{"name":"Betania Evangelical Hospital  Naples 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