{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:18:03Z","timestamp":1787015883637,"version":"build-2736575974"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,5,21]],"date-time":"2013-05-21T00:00:00Z","timestamp":1369094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Legumes, and particularly lentils, are frequently consumed in\n                      <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>\n                      editerranean,\n                      <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>\n                      iddle\n                      <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                      astern, and some\n                      <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\n                      sian countries. The aim of this study was to document the demographic features of children with lentil allergy and to determine the role of specific\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      g\n                      <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                      (s\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      g\n                      <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                      ) in predicting the risk of clinical reactivity and disease persistence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Thirty children were enrolled. The diagnosis of lentil allergy was based on convincing history of symptoms or anaphylaxis after the ingestion of lentils, with positive skin tests and\/or s\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      g\n                      <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                      to lentils. To determine the diagnosis and prognosis of lentil allergy, 24 children were evaluated with food challenges.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median age at the onset of symptoms was 1.5\u00a0yr (0.9\u20132.3) (inter\u2010quartile range). The most frequent symptoms were immediate cutaneous (97%) and respiratory (30%) reactions, whereas eight patients (27%) reported anaphylactic reactions. The median level of lentil s\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      g\n                      <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                      at the time of diagnosis was 3\u00a0kU\/l (1.2\u20139.6). Of the 24 challenges, 12 were positive. Fifteen patients (50%) outgrew the lentil allergy by the age of 3.5 (2.5\u201311) years. Children with an initial lentil s\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      g\n                      <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                      \u00a0&lt;\u00a04.9\u00a0kU\/l had a significantly higher likelihood (68.4% vs. 18.2%) of outgrowing the lentil allergy than children with an initial lentil s\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      g\n                      <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                      \u00a0\u2265\u00a04.9 k\/l (p\u00a0=\u00a00.008).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Our results suggest that s\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      g\n                      <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                      levels may be important for predicting clinical reactivity and persistence of lentil allergy.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pai.12080","type":"journal-article","created":{"date-parts":[[2013,5,21]],"date-time":"2013-05-21T05:09:02Z","timestamp":1369112942000},"page":"382-388","source":"Crossref","is-referenced-by-count":17,"title":["Role of specific\n                    <scp>I<\/scp>\n                    g\n                    <scp>E<\/scp>\n                    in predicting the clinical course of lentil allergy in children"],"prefix":"10.1111","volume":"24","author":[{"given":"Suleyman T.","family":"Yavuz","sequence":"first","affiliation":[{"name":"Department of Pediatric Allergy Hacettepe University School of Medicine Ankara 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Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozlem","family":"Cavkaytar","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy Hacettepe University School of Medicine Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdem","family":"Karabulut","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Hacettepe University School of Medicine Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cansin","family":"Sackesen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy Hacettepe University School of Medicine Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,5,21]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"Food and Agricultural Organization of United Nations: Economic And Social Department: The Statistical 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