{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T15:53:50Z","timestamp":1777650830522,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,12,2]],"date-time":"2013-12-02T00:00:00Z","timestamp":1385942400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To date, extensive research has been undertaken on a potential link of breastfeeding (<jats:styled-content style=\"fixed-case\">BF<\/jats:styled-content>) to wheezing illnesses. Nevertheless, an association remains to be established, partly due to age\u2010dependent discrepancies and different definitions of exposures\/outcomes across studies. We thus investigated the relation of diverse infantile feeding patterns with wheeze\/asthma prevalence in two cohorts of children of different ages (preschool and preadolescent).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Wheeze ever\/in the last 12\u00a0months (current) and doctor\u2010diagnosed asthma were retrospectively reported by parents of the participants of two cross\u2010sectional studies: the <jats:italic>Genesis<\/jats:italic> study (1871 children aged 1\u20135) and the <jats:italic>Healthy Growth<\/jats:italic> study (1884 children aged 9\u201313). Information on feeding practices (exclusive breastfeeding vs. mixed vs. formula feeding) and their duration (2 vs. 4 vs. 6\u00a0months) was recorded. Perinatal and anthorpometric data were also collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In pre\u2010schoolers, regimes that did not entail exclusive <jats:styled-content style=\"fixed-case\">BF<\/jats:styled-content> were positively correlated to current\/ever wheeze, both before and after adjustment for confounders. No differences between the associations of regimes with 2, 4 or 6\u00a0months of exclusive <jats:styled-content style=\"fixed-case\">BF<\/jats:styled-content> with current\/ever wheeze were shown. Furthermore, there was no consistent correlation of feeding practices with physician\u2010diagnosed asthma. In pre\u2010adolescents, no association of infantile feeding patterns with the wheeze\/asthma outcomes was observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Exclusive <jats:styled-content style=\"fixed-case\">BF<\/jats:styled-content> is associated with reduced prevalence of current\/ever wheeze in pre\u2010schoolers; however, this appears to wane in older children. The association of a period of exclusive <jats:styled-content style=\"fixed-case\">BF<\/jats:styled-content> as low as 2\u00a0months with pre\u2010school wheeze prevalence, appeared to be comparable with that of 6\u00a0months of exclusivity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pai.12169","type":"journal-article","created":{"date-parts":[[2013,12,3]],"date-time":"2013-12-03T02:28:42Z","timestamp":1386037722000},"page":"772-781","source":"Crossref","is-referenced-by-count":14,"title":["Breastfeeding and wheeze prevalence in pre\u2010schoolers and pre\u2010adolescents: the <i><scp>G<\/scp>enesis<\/i> and <i><scp>H<\/scp>ealthy <scp>G<\/scp>rowth<\/i> studies"],"prefix":"10.1111","volume":"24","author":[{"given":"George V.","family":"Guibas","sequence":"first","affiliation":[{"name":"Allergy Department 2nd Pediatric Clinic University of Athens Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paraskevi","family":"Xepapadaki","sequence":"additional","affiliation":[{"name":"Allergy Department 2nd Pediatric Clinic University of Athens Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Moschonis","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics Harokopio University of Athens Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos","family":"Douladiris","sequence":"additional","affiliation":[{"name":"Allergy Department 2nd Pediatric Clinic University of Athens Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amalia","family":"Filippou","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics Harokopio University of Athens Athens 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