{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T18:27:52Z","timestamp":1790360872058,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,11,9]],"date-time":"2014-11-09T00:00:00Z","timestamp":1415491200000},"content-version":"vor","delay-in-days":39,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Many studies have investigated individual nutrients or foods as risk factors for allergic disease, but few have studied dietary patterns. We aimed to use principal component analysis (<jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content>) to determine dietary patterns in school age children and examine associations between these dietary patterns and wheeze, asthma and sensitization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants in a population\u2010based birth cohort attended review clinics at ages 8 and 11\u00a0yr. A validated questionnaire was interviewer\u2010administered to collect information on parentally reported symptoms and doctor\u2010diagnosed asthma. Atopic sensitization was ascertained by skin\u2010prick tests. Current asthma was defined as doctor\u2010diagnosed asthma <jats:italic>and<\/jats:italic> wheezing in the previous 12\u00a0months. A validated semi\u2010quantitative food frequency questionnaire was completed at age 8\u00a0yr, and <jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content> was used to determine dietary patterns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Principal component analysis identified three dietary components, which based on their characteristics we termed as <jats:italic>Traditional<\/jats:italic> (mixed meat, fish, fruit and vegetables), <jats:italic>Western<\/jats:italic> (predominantly high fat content, processed foods) and <jats:italic>Other<\/jats:italic> (predominantly grains and nuts) dietary patterns. High adherence to the <jats:italic>Western<\/jats:italic> diet pattern was significantly associated with doctor\u2010diagnosed asthma and current asthma at age 8\u00a0yr [<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content> (95% CI): 2.19 (1.20\u20134.01), p\u00a0=\u00a00.01; 2.59 (1.15\u20135.81), p\u00a0=\u00a00.02; respectively]. A similar association was found for current asthma at age 11\u00a0yr [<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content> (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>): 2.20 (1.07\u20134.51), p\u00a0=\u00a00.03]. There was no evidence of an association between dietary patterns and current wheeze and allergic sensitization at either age 8 or 11\u00a0yr.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>School age children adhering strongly to a <jats:italic>Western<\/jats:italic> diet, high in fat and processed foods, had a higher risk of current asthma and doctor\u2010diagnosed asthma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pai.12276","type":"journal-article","created":{"date-parts":[[2014,9,9]],"date-time":"2014-09-09T08:06:07Z","timestamp":1410249967000},"page":"565-571","source":"Crossref","is-referenced-by-count":39,"title":["Cross\u2010sectional association of dietary patterns with asthma and atopic sensitization in childhood \u2013 in a cohort study"],"prefix":"10.1111","volume":"25","author":[{"given":"Sumaiya","family":"Patel","sequence":"first","affiliation":[{"name":"School of Social and Community Medicine University of Bristol Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Custovic","sequence":"additional","affiliation":[{"name":"Centre of Respiratory and Allergy Institute Of Inflammation and Repair Manchester Academic Health Science Centre The University of Manchester University Hospital of South Manchester NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaclyn A.","family":"Smith","sequence":"additional","affiliation":[{"name":"Centre of Respiratory and Allergy Institute Of Inflammation and Repair Manchester Academic Health Science Centre The University of Manchester University Hospital of South Manchester NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Simpson","sequence":"additional","affiliation":[{"name":"Centre of Respiratory and Allergy Institute Of Inflammation and Repair Manchester Academic Health Science Centre The University of Manchester University Hospital of South Manchester NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gina","family":"Kerry","sequence":"additional","affiliation":[{"name":"Centre of Respiratory and Allergy Institute Of Inflammation and Repair Manchester Academic Health Science Centre The University of Manchester University Hospital of South Manchester NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare S.","family":"Murray","sequence":"additional","affiliation":[{"name":"Centre of Respiratory and Allergy Institute Of Inflammation and Repair Manchester Academic Health Science Centre The University of Manchester University Hospital of South Manchester NHS Foundation Trust Manchester 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