{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T22:39:18Z","timestamp":1708555158856},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,1,26]],"date-time":"2016-01-26T00:00:00Z","timestamp":1453766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002560","name":"Soonchunhyang University","doi-asserted-by":"publisher","award":["20120674"],"award-info":[{"award-number":["20120674"]}],"id":[{"id":"10.13039\/501100002560","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although rhinitis is the most common allergic disease in children, few studies have explored the causal relationships between mould allergens and rhinitis. Thus, this study aimed to identify factors, especially prior exposure to mould allergens, related to rhinitis and rhinoconjunctivitis in Korean children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Subjects in this study were 12\u2010 to 13\u2010year\u2010old children from 40 national middle schools who were participants of the International Study of Asthma and Allergies in Childhood (<jats:styled-content style=\"fixed-case\">ISAAC<\/jats:styled-content>) study in Korea. A total of 3852 children who completed the <jats:styled-content style=\"fixed-case\">ISAAC<\/jats:styled-content> questionnaire in 2010 and underwent a skin prick test (<jats:styled-content style=\"fixed-case\">SPT<\/jats:styled-content>) and blood test were enrolled in this study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of symptoms suggestive of rhinitis or rhinoconjunctivitis in last 12 months was 42.7% and 19.4%, respectively. A parental history of allergies (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 2.03, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> = 1.75\u20132.35; <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 2.55, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> = 2.13\u20133.06), visible mould or dampness (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 1.28, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> = 1.09\u20131.51; <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 1.23, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> = 1.00\u20131.51), previous exposure to mould allergens (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 4.53, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> = 2.32\u20138.84; <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 4.98, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> = 2.43\u201310.20), total IgE levels \u226578 <jats:styled-content style=\"fixed-case\">kU<\/jats:styled-content>\/l (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 1.44, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> = 1.22\u20131.69; <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 1.99, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> = 1.60\u20132.48) were risk factors for rhinitis and rhinoconjunctivitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study suggested that previous exposure to mould allergens more influenced rhinitis and rhinoconjunctivitis than visible mould or dampness, and that total IgE levels of \u226578 <jats:styled-content style=\"fixed-case\">kU<\/jats:styled-content>\/l, which was the criterion suggested in a study of Asian children, were risk factors for rhinitis diseases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pai.12520","type":"journal-article","created":{"date-parts":[[2015,12,12]],"date-time":"2015-12-12T18:32:42Z","timestamp":1449945162000},"page":"290-298","source":"Crossref","is-referenced-by-count":8,"title":["Exposure to mould allergens and rhinoconjunctivitis in Korean children"],"prefix":"10.1111","volume":"27","author":[{"given":"Myung\u2010Il","family":"Hahm","sequence":"first","affiliation":[{"name":"Department of Health Administration and Management College of Medical Science Soonchunhyang University Asan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jihyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Samsung Medical Center Environmental Health Center for Atopic Diseases Sungkyunkwan University School of Medicine Seoul 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