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To date, available data on <jats:styled-content style=\"fixed-case\">LAR<\/jats:styled-content> are mostly focused on adults. The purpose of this \u2018Rostrum\u2019 was to critically discuss data and implications of the \u2018<jats:styled-content style=\"fixed-case\">LAR<\/jats:styled-content> concept\u2019 in paediatrics. In the natural history of rhinitis due to IgE\u2010mediated reactions triggered by exposure to allergens, a \u2018<jats:styled-content style=\"fixed-case\">LAR<\/jats:styled-content>\u2019 can be either the initial, transient stage of classical allergic rhinitis or a stable phenotype never evolving to \u2018systemic\u2019 IgE sensitization. Given the present difficulties in performing routinely nasal allergen provocation test in children, the development of sensitive and specific tests to detect IgE in the child's nasal secretions is a research priority. We suggest also the hypothetical role of allergen immunoprophylaxis or immunotherapy in <jats:styled-content style=\"fixed-case\">LAR<\/jats:styled-content>. Last, the term \u2018local allergic rhinitis\u2019 may be inappropriate, as rhinitis is always \u2018local\u2019, while IgE sensitization can be either \u2018local\u2019 or \u2018systemic\u2019.<\/jats:p>","DOI":"10.1111\/pai.12577","type":"journal-article","created":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T12:22:58Z","timestamp":1461241378000},"page":"569-573","source":"Crossref","is-referenced-by-count":18,"title":["Local allergic rhinitis: A critical reappraisal from a paediatric perspective"],"prefix":"10.1111","volume":"27","author":[{"given":"Stefania","family":"Arasi","sequence":"first","affiliation":[{"name":"Allergy Unit Department of Pediatrics University of Messina Messina Italy"},{"name":"Molecular Allergology and Immunomodulation Department of Pediatric Pneumology and Immunology Charit\u00e9 Medical University Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni 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