{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:32:24Z","timestamp":1790814744067,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,7,15]],"date-time":"2016-07-15T00:00:00Z","timestamp":1468540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Allergic diseases are common chronic diseases in children and adolescents, but limited epidemiological data are available during transition into adulthood. Nasal <jats:italic>Staphylococcus aureus<\/jats:italic> carriage has been linked to increased prevalence of allergic disease. The objective of this study was to define the prevalence of allergic diseases in adolescents above the Arctic Circle in Northern Norway and to study the associations of <jats:italic>S. aureus<\/jats:italic> carriage with allergic diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A school\u2010based cohort in late adolescence (18\u201319 years) was invited to participate in a cross\u2010sectional study on lifestyle and health, and 868 attended (71.9%). Self\u2010reported allergic disease and severity of eczema were assessed by Mechanisms of the Development of Allergy and Patient\u2010Oriented Eczema Measure questionnaires. Participants were tested with spirometry and exhaled nitric oxide (FeNO) and swabbed for bacterial culture from nose and eczematous skin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found asthma, eczema, allergic rhinitis (AR), and nasal <jats:italic>S. aureus<\/jats:italic> carriage among 11.9%, 10.4%, 26.0%, and 51.3% of the participants, respectively, and 10.2% had allergic multimorbidity. Lifetime prevalence for any allergic disease was 45.1%. Reduced lung function and increased FeNO were found in 11.6% and 22.1% in participants with asthma, respectively. Nasal <jats:italic>S. aureus<\/jats:italic> carriage was associated with eczema, severe asthma, and severe AR. FeNO &gt; 25 ppb was associated with both asthma and nasal <jats:italic>S. aureus<\/jats:italic> carriage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Asthma, eczema, and AR are common among adolescents above the Arctic Circle in Norway. Allergic disease is associated with <jats:italic>S. aureus<\/jats:italic> carriage, but its role in the pathogenesis and severity is not established.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pai.12595","type":"journal-article","created":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T04:37:48Z","timestamp":1463459868000},"page":"728-735","source":"Crossref","is-referenced-by-count":22,"title":["Allergic disease and <i>Staphylococcus aureus<\/i> carriage in adolescents in the Arctic region of Norway"],"prefix":"10.1111","volume":"27","author":[{"given":"Martin","family":"S\u00f8rensen","sequence":"first","affiliation":[{"name":"Department of Paediatric and Adolescent medicine University Hospital of North Norway Troms\u00f8 Norway"},{"name":"Paediatric Research Group Department of Clinical Medicine UiT, The Arctic University of Norway Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Wickman","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden"},{"name":"Sachs' Children's Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna U. 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