{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T15:22:37Z","timestamp":1785338557688,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T00:00:00Z","timestamp":1549843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","award":["GR-2009-1595946"],"award-info":[{"award-number":["GR-2009-1595946"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Schoolchildren screening for allergic diseases may improve early identification and management of atopic children. The aim of this study was to perform a schoolchildren screening program for identification of children with allergic diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All parents of children attending to 13 primary schools in the city of Rome were requested to fill in a demographic data form and the ChAt questionnaire. Allergological evaluation was performed in the children with suspect of allergy (ChAt score\u00a0&gt;\u00a02). Ocular examination was performed to identify signs of allergic conjunctivitis. The presence of allergic symptoms was related to demographic and environmental variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 2667 children (mean age: 7.1\u00a0\u00b1\u00a01\u00a0years) were included, and 2489 (93.3%) parents completed the ChAt questionnaire. Results of ChAt questionnaire showed a previous diagnosis of allergic disease in 637 (25.6%) children and the potential presence of an allergic disease (ChAt score\u00a0&gt;\u00a02) in 35.1%. Multivariate analysis showed that older age, male gender, and having less than two siblings were associated with higher risk of allergic disease. Visual screening showed the presence of clinical signs of allergic conjunctivitis in 2% of children. Allergologic evaluation in 334 children confirmed the diagnosis of allergic disease in 324 (97%) cases. Among them, 97 (29.9%) did not refer to a previous formal diagnosis of allergic condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study confirmed that schoolchildren screening using ChAt questionnaire could represent a useful tool for early identification of yet undiagnosed atopic children.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pai.13024","type":"journal-article","created":{"date-parts":[[2019,1,25]],"date-time":"2019-01-25T12:08:03Z","timestamp":1548418083000},"page":"289-295","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Allergy screening in a schoolchildren\u2010based population"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5569-778X","authenticated-orcid":false,"given":"Marta","family":"Sacchetti","sequence":"first","affiliation":[{"name":"Department of Sense Organs University Sapienza of Rome Rome Italy"},{"name":"Cornea and Ocular Surface Unit San Raffaele Hospital Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenza","family":"Regine","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases National Institute of Health Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Mantelli","sequence":"additional","affiliation":[{"name":"Department of Biology, College of Science and Technology Temple University Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loredana","family":"Chini","sequence":"additional","affiliation":[{"name":"Pediatric Immunopathology and Allergology Unit, Policlinico Tor Vergata University of Rome Tor Vergata Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviana","family":"Moschese","sequence":"additional","affiliation":[{"name":"Pediatric Immunopathology and Allergology Unit, Policlinico Tor Vergata University of Rome Tor Vergata Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Bonini","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute Royal Brompton Hospital &amp; Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Pugliese","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases National Institute of Health Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Suligoi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases National Institute of Health Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Lambiase","sequence":"additional","affiliation":[{"name":"Department of Sense Organs University Sapienza of Rome Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,11]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Immunobiology: The Immune System in Health and Disease","author":"Janeway C","year":"2001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69283-0"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2017.10.037"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12867"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2009.10.002"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2015.7.1.44"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2004.00526.x"},{"issue":"10","key":"e_1_2_7_9_1","first-page":"517","article-title":"[Direct and indirect costs associated with respiratory allergic diseases in Italy. A probabilistic cost of illness study]","volume":"106","author":"Marcellusi A","year":"2015","journal-title":"Recenti Prog Med"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40413-015-0067-y"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)61445-7"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/02770903.2011.563808"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.06.028"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.2147\/PHMT.S142271"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/02770900801890315"},{"key":"e_1_2_7_16_1","first-page":"CD005023","article-title":"Vision screening for correctable visual acuity deficits in school\u2010age children and adolescents","volume":"2","author":"Evans JR","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"issue":"5","key":"e_1_2_7_17_1","first-page":"383","article-title":"High prevalence of asthma and allergic diseases in children aged 6 to [corrected] 7 years from the Canary Islands. [corrected]","volume":"19","author":"Sanchez\u2010Lerma B","year":"2009","journal-title":"J Investig Allergol Clin Immunol"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)61842-X"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2007.00601.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2008.00793.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/2045-7022-2-21"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2005.05.012"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1999.tb01072.x"},{"key":"e_1_2_7_24_1","article-title":"Hygiene hypothesis in asthma development: is hygiene to blame?","author":"Tilburg BE","year":"2017","journal-title":"Arch Med Res"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.56.3.209"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.299.6710.1259"},{"issue":"1","key":"e_1_2_7_27_1","first-page":"49","article-title":"Allergic conjunctivitis: current concepts on pathogenesis and management","volume":"32","author":"Sacchetti M","year":"2018","journal-title":"J Biol Regul Homeost Agents"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0000000000000100"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.11.043"},{"key":"e_1_2_7_30_1","first-page":"311","article-title":"Allergic eye disorders","volume":"16","author":"Bielory L","year":"2002","journal-title":"Clin Allergy Immunol"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2004.00613.x"}],"container-title":["Pediatric Allergy and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpai.13024","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pai.13024","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pai.13024","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pai.13024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T00:40:43Z","timestamp":1694306443000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pai.13024"}},"subtitle":[],"editor":[{"given":"Jon","family":"Genuneit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,2,11]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1111\/pai.13024"],"URL":"https:\/\/doi.org\/10.1111\/pai.13024","archive":["Portico"],"relation":{},"ISSN":["0905-6157","1399-3038"],"issn-type":[{"value":"0905-6157","type":"print"},{"value":"1399-3038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,11]]},"assertion":[{"value":"2018-06-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}