{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T03:35:44Z","timestamp":1777952144133,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T00:00:00Z","timestamp":1583884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cashew nut (CN) allergy prevalence has increased over the last few years. In children allergic to CN, complete avoidance of pistachio is usually recommended, but recent study showed that only one third of children allergic to CN were also allergic to pistachio. The aim of our study was to identify predictive factors of allergy to pistachio in children allergic to CN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All children who had a positive oral food challenge (OFC) to CN between November 2013 and October 2017 in the Paediatric Allergy Department of the University Hospital of Nancy were included. Logistic regression models were used to predict the probability of allergy to pistachio.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 147 children included, tolerance or allergy to pistachio was known for 51. Out of these, 40 were allergic to pistachio (78.4%). Children allergic to pistachio had a larger weal size of skin prick test to CN (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.01) and pistachio (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.0007) and a lower reaction dose to CN (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001). In multivariate analysis, only the reaction dose to CN was significantly associated with allergy to pistachio. Children with a low reaction dose to CN were significantly more at risk to have an allergy to pistachio (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A low reaction dose to CN seems to be a predictive factor of allergy to pistachio in children allergic to CN. In order to limit unnecessary food eviction, a pistachio OFC should be performed in children having high reaction dose whatever the importance of the skin or the specific IgE sensitization to pistachio.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pai.13238","type":"journal-article","created":{"date-parts":[[2020,3,3]],"date-time":"2020-03-03T07:01:26Z","timestamp":1583218886000},"page":"506-514","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Predictive factors of allergy to pistachio in children allergic to cashew nut"],"prefix":"10.1111","volume":"31","author":[{"given":"Lucile","family":"Saba","sequence":"first","affiliation":[{"name":"Pediatric Allergy Department Children\u2019s Hospital University Hospital of Nancy Vandoeuvre les Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Clerc\u2010Urm\u00e8s","sequence":"additional","affiliation":[{"name":"Clinical Research Support Facility PARC UMDS University Hospital of Nancy Vandoeuvre les Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9mence","family":"Delahaye","sequence":"additional","affiliation":[{"name":"Pediatric Allergy Department Children\u2019s Hospital University Hospital of Nancy Vandoeuvre les Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilie","family":"Chevillot","sequence":"additional","affiliation":[{"name":"Pediatric Allergy Department Children\u2019s Hospital University Hospital of Nancy Vandoeuvre les Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Jarlot\u2010Chevaux","sequence":"additional","affiliation":[{"name":"Pediatric Allergy Department Children\u2019s Hospital University Hospital of Nancy Vandoeuvre les Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascale","family":"Dumond","sequence":"additional","affiliation":[{"name":"Pediatric Allergy Department Children\u2019s Hospital University Hospital of Nancy Vandoeuvre les Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cyril","family":"Schweitzer","sequence":"additional","affiliation":[{"name":"Department of Pediatric Lung Function Testing Children\u2019s Hospital University Hospital of Nancy Vandoeuvre les Nancy France"},{"name":"EA 3450 DevAH\u2010Department of Physiology Faculty of Medicine University of Lorraine Vandoeuvre les Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2492-9864","authenticated-orcid":false,"given":"Amandine","family":"Divaret\u2010Chauveau","sequence":"additional","affiliation":[{"name":"Pediatric Allergy Department Children\u2019s Hospital University Hospital of Nancy Vandoeuvre les Nancy France"},{"name":"EA 3450 DevAH\u2010Department of Physiology Faculty of Medicine University of Lorraine Vandoeuvre les Nancy France"},{"name":"UMR\/CNRS 6249 Chrono\u2010environnement University of Franche Comt\u00e9 Besan\u00e7on France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,3,11]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02057"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.05.041"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01447.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.13150"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2017.1379947"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.13163"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2017.10.132"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12401"},{"issue":"3","key":"e_1_2_7_10_1","first-page":"173","article-title":"Allergy to Anacardiaceae: description of cashew and pistachio nut allergens","volume":"10","author":"Garc\u00eda F","year":"2000","journal-title":"J Investig Allergol Clin Immunol"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2008.02998.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12826"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2019.09.036"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414850"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318054b0c3"},{"key":"e_1_2_7_16_1","unstructured":"Ciqual Table de composition nutritionnelle des aliments.https:\/\/ciqual.anses.fr\/. 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