{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T05:25:44Z","timestamp":1784352344225,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T00:00:00Z","timestamp":1598227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chronic inducible urticaria (CIndU) is a subtype of chronic urticaria induced by a physical stimulus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the clinical features, prognostic factors, and natural course of childhood CIndU subtypes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients (1\u201018\u00a0years old, n\u00a0=\u00a0117) diagnosed with CIndU between March 2011 and March 2019 were analyzed. Patients (n\u00a0=\u00a0101) were re\u2010evaluated for the status of their CIndU at least 6\u00a0months after the initial evaluation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The study population comprised of 117 children with a median (inter\u2010quartile range) age of 10.3 (6\u201014.8) years at admission and a male predominance (53%). Symptomatic dermographism was the most common type of CIndU, affecting 65% of the group, followed by cold urticaria and cholinergic urticaria, which affected 17% and 15.4%, respectively. Baseline serum tryptase levels in cholinergic urticaria and cold urticaria were higher than those in symptomatic dermographism [7.0 (3.3\u201010.7) \u03bcg\/L, 4.2 (2.8\u20109.3) \u03bcg\/L, and 2.7\u00a0\u03bcg\/L (1.8\u20105.9), respectively;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.020]. Recovery was observed in 9.6%, 25.3%, and 34.7% of the CIndU children after 12, 36, and 60\u00a0months, respectively. Of the patients with symptomatic dermographism, 40% had remission in 5\u00a0years, whereas this rate was only one\u2010fifth in patients with cold urticaria. The worst prognosis was observed in patients with cholinergic urticaria.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study concluded that nearly one\u2010third of children with CIndU recovered within 5\u00a0years and symptomatic dermographism has the best prognosis. Cholinergic urticaria is the CIndU type with the worst prognosis, male dominance, and highest baseline serum tryptase levels.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pai.13324","type":"journal-article","created":{"date-parts":[[2020,8,2]],"date-time":"2020-08-02T01:30:56Z","timestamp":1596331856000},"page":"146-152","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Chronic inducible urticaria subtypes in children: Clinical features and prognosis"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4132-5349","authenticated-orcid":false,"given":"Fatma","family":"Bal","sequence":"first","affiliation":[{"name":"Department of Pediatrics Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7841-4690","authenticated-orcid":false,"given":"Melike","family":"Kahveci","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7444-251X","authenticated-orcid":false,"given":"Ozge","family":"Soyer","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7402-6850","authenticated-orcid":false,"given":"Bulent Enis","family":"Sekerel","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy Hacettepe University Faculty of Medicine Ankara 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