{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:36:02Z","timestamp":1787499362674,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001048","name":"Asthma Foundation of Victoria","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001048","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP454856"],"award-info":[{"award-number":["APP454856"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Early life body mass index (BMI) trajectories influence the risk of asthma at 18 years of age. However, it is unclear if these are also associated with other allergic diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We investigated the associations between BMI trajectories and subsequent allergic rhinitis, eczema and food sensitisation\/allergies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Parent\u2010reported anthropometric data were collected 18 times in the first two years of life from a cohort of 620 participants in a high\u2010risk cohort. Group\u2010based trajectory modelling was applied to develop BMI trajectories. Associations between trajectories and allergic rhinitis, eczema and food sensitisation at 6, 12 and 18 years of age were assessed using logistic regression models. Potential effect modifications by parental allergic disease, sex and allocated infant formula were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified five BMI trajectories: average, below average, persistently low, early low and catch up, and persistently high. None showed an association with allergic rhinitis. In participants with maternal allergic rhinitis, \u2018early\u2010low and catch\u2010up\u2019 (OR\u00a0=\u00a02.83;95%CI 1.34\u20105.96, P\n                      <jats:sub>int<\/jats:sub>\n                      \u00a0=\u00a00.05) and \u2018below average\u2019 trajectories (OR\u00a0=\u00a02.39; 1.18\u20107.23, P\n                      <jats:sub>int<\/jats:sub>\n                      \u00a0=\u00a00.02) were associated with allergic rhinitis at 18 years of age compared with the average trajectory. No associations were observed with eczema or food sensitisation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Infants with early\u2010low and catch\u2010up, or below average BMI growth, were at increased risk of allergic rhinitis at 18 years if they had a mother with allergic rhinitis. These results require replication, but suggest that interactions between poor intrauterine growth, failure to thrive and maternal allergies may influence the risk of allergic rhinitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pai.13765","type":"journal-article","created":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T04:44:46Z","timestamp":1647924286000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Associations between Body Mass Index Trajectories in the first two years of life and Allergic Rhinitis, Eczema and Food Allergy outcomes up to early adulthood"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2597-0842","authenticated-orcid":false,"given":"Chia\u2010Lun","family":"Chang","sequence":"first","affiliation":[{"name":"Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics Melbourne School of Population and Global Health University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7376-9561","authenticated-orcid":false,"given":"Gulshan Bano","family":"Ali","sequence":"additional","affiliation":[{"name":"Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics Melbourne School of Population and Global Health University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2342-3888","authenticated-orcid":false,"given":"Caroline J.","family":"Lodge","sequence":"additional","affiliation":[{"name":"Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics Melbourne School of Population and Global Health University of Melbourne  Melbourne Australia"},{"name":"Murdoch Children's Research Institute Royal Children's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9954-0538","authenticated-orcid":false,"given":"Michael J.","family":"Abramson","sequence":"additional","affiliation":[{"name":"School of Public Health &amp; Preventive Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9597-418X","authenticated-orcid":false,"given":"Bircan","family":"Erbas","sequence":"additional","affiliation":[{"name":"School of Psychology and Public Health La Trobe University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3839-5293","authenticated-orcid":false,"given":"Mimi L. K.","family":"Tang","sequence":"additional","affiliation":[{"name":"Allergy Immunology, Murdoch Children's Research Institute  Melbourne Victoria Australia"},{"name":"Department of Allergy Immunology Royal Children\u2019s Hospital  Melbourne Victoria Australia"},{"name":"Department of Paediatrics University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8512-5192","authenticated-orcid":false,"given":"Cecilie","family":"Svanes","sequence":"additional","affiliation":[{"name":"Centre for International Health University of Bergen  Bergen Norway"},{"name":"Department of Occupational Medicine Haukeland University Hospital  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4388-784X","authenticated-orcid":false,"given":"Dinh Son","family":"Bui","sequence":"additional","affiliation":[{"name":"Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics Melbourne School of Population and Global Health University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6063-1937","authenticated-orcid":false,"given":"Shyamali C.","family":"Dharmage","sequence":"additional","affiliation":[{"name":"Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics Melbourne School of Population and Global Health University of Melbourne  Melbourne Australia"},{"name":"Murdoch Children's Research Institute Royal Children's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4691-8162","authenticated-orcid":false,"given":"Adrian J.","family":"Lowe","sequence":"additional","affiliation":[{"name":"Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics Melbourne School of Population and Global Health University of Melbourne  Melbourne Australia"},{"name":"Murdoch Children's Research Institute Royal Children's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jan.12129"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14879"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-018-1093-z"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech-2014-203808"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.01.001"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2021.02.020"},{"key":"e_1_2_10_8_1","first-page":"1","article-title":"Sex\u2010specific association between childhood BMI trajectories and asthma phenotypes. 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