{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T02:14:13Z","timestamp":1783649653203,"version":"3.55.0"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T00:00:00Z","timestamp":1653350400000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2008\u2010E33030\u201000"],"award-info":[{"award-number":["2008\u2010E33030\u201000"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2009\u2010E33033\u201000"],"award-info":[{"award-number":["2009\u2010E33033\u201000"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2011\u2010E33021\u201000"],"award-info":[{"award-number":["2011\u2010E33021\u201000"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2012\u2010E33012\u201000"],"award-info":[{"award-number":["2012\u2010E33012\u201000"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2013\u2010E51003\u201000"],"award-info":[{"award-number":["2013\u2010E51003\u201000"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2014\u2010E51004\u201000"],"award-info":[{"award-number":["2014\u2010E51004\u201000"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2014\u2010E51004\u201001"],"award-info":[{"award-number":["2014\u2010E51004\u201001"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2014\u2010E51004\u201002"],"award-info":[{"award-number":["2014\u2010E51004\u201002"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2017\u2010E67002\u201000"],"award-info":[{"award-number":["2017\u2010E67002\u201000"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2017\u2010E67002\u201001"],"award-info":[{"award-number":["2017\u2010E67002\u201001"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["2017\u2010E67002\u201002"],"award-info":[{"award-number":["2017\u2010E67002\u201002"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF\u20102020R1A2C2012822"],"award-info":[{"award-number":["NRF\u20102020R1A2C2012822"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The level of pollen in Korea has increased over recent decades. Research suggests that oral allergy syndrome (OAS) may be more frequent in childhood than previously recognized. We aimed to investigate the prevalence and characteristics of OAS in children aged 6\u201310\u00a0years from a general\u2010population\u2010based birth cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed 930 children from the cohort for childhood origin of asthma and allergic diseases (COCOA). Allergic diseases were diagnosed annually by pediatric allergists. The skin prick tests were performed with 14 common inhalant allergens and four food allergens for the general population of children aged 3 and 7\u00a0years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 930 eligible children, 44 (4.7%) aged 6\u201310\u00a0years were diagnosed with OAS. The mean age at onset was 6.74\u00a0years. OAS prevalence was 7.2% among children with allergic rhinitis (AR) and 19.1% among those with pollinosis, depending on comorbidity. OAS was more prevalent in schoolchildren with atopic dermatitis, food allergy, and sensitization to food allergens and grass pollen in early childhood. In schoolchildren with AR, only a history of food allergy until the age of 3\u00a0years increased the risk of OAS (aOR 2.971, 95% CI: 1.159\u20137.615).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Food allergy and food sensitization in early childhood were associated with OAS in schoolchildren with AR. Further study is required to elucidate the mechanism by which food allergy in early childhood affects the development of OAS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pai.13786","type":"journal-article","created":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T09:09:30Z","timestamp":1653383370000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Food allergy in early childhood increases the risk of oral allergy syndrome in schoolchildren: A birth cohort study"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6981-6292","authenticated-orcid":false,"given":"Kun\u2010Baek","family":"Song","sequence":"first","affiliation":[{"name":"Department of Pediatrics Childhood Asthma Atopy Center Humidifier Disinfectant Health Center Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0891-1311","authenticated-orcid":false,"given":"Min Jee","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Uijeongbu Eulji Medical Center Eulji University School of Medicine  Uijeongbu Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1122-1592","authenticated-orcid":false,"given":"Eom Ji","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Childhood Asthma Atopy Center Humidifier Disinfectant Health Center Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0559-4982","authenticated-orcid":false,"given":"Sungsu","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Pusan National University Yangsan Hospital  Yangsan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jisun","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Chung\u2010Ang University Hospital Chung\u2010Ang University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun\u2010Ju","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Pediatrics International St. Mary's Hospital Catholic Kwandong University College of Medicine  Incheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3562-3916","authenticated-orcid":false,"given":"Bong\u2010Seong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Gangneung Asan Hospital University of Ulsan College of Medicine  Gangneung Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7751-9829","authenticated-orcid":false,"given":"Kangmo","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4529-6135","authenticated-orcid":false,"given":"Kyung Won","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Severance Children's Hospital Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3227-5511","authenticated-orcid":false,"given":"Youn Ho","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics CHA Gangnam Medical Center CHA University School of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7817-8728","authenticated-orcid":false,"given":"Dong In","family":"Suh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seoul National University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1409-2113","authenticated-orcid":false,"given":"Soo\u2010Jong","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Childhood Asthma Atopy Center Humidifier Disinfectant Health Center Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2499-0702","authenticated-orcid":false,"given":"So\u2010Yeon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Childhood Asthma Atopy Center Humidifier Disinfectant Health Center Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(03)02008-6"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2542-5196(19)30015-4"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/pai.13435"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080147"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2012.4.1.5"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2018.00273"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1994.tb00248.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1982.tb02323.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2018.10.6.648"},{"key":"e_1_2_10_11_1","first-page":"650","article-title":"Oral allergy syndrome in patients with pollen allergies in Korea: a multicenter cross\u2010sectional study","volume":"73","author":"Choi J","year":"2018","journal-title":"Allergy"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.4168\/aard.2018.6.4.219"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2019.07.022"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2008.00842.x"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0249649"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.14742"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2018.33.e218"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2466-14-109"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)07302-9"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.01.031"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2008.01672.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcps.2012.03.006"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/pai.12136"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/idj.12164"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.12104"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2018.08.010"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2019.34.e11"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.alit.2019.09.008"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1987.tb02317.x"}],"container-title":["Pediatric Allergy and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pai.13786","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pai.13786","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pai.13786","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T11:18:56Z","timestamp":1692789536000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pai.13786"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1111\/pai.13786"],"URL":"https:\/\/doi.org\/10.1111\/pai.13786","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/PAI.13786\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/PAI.13786\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/PAI.13786\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/PAI.13786\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/PAI.13786\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/PAI.13786\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/PAI.13786\/v2\/response1","asserted-by":"object"}]},"ISSN":["0905-6157","1399-3038"],"issn-type":[{"value":"0905-6157","type":"print"},{"value":"1399-3038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"2021-12-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13786"}}