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The dietary inflammatory index (DII) is a tool to assess the inflammatory potential of the diet and has been suggested to be associated with offspring allergy development. Its association with food allergy and immunoglobulin E (IgE) sensitization in children remains understudied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study analyzed 4709 mother\u2010partner\u2010child triads from the NorthPop Birth Cohort in Sweden. Maternal DII scores were calculated from a food frequency questionnaire administered at gestational week 34. Allergy outcomes at 18\u2009months included parent\u2010reported physician\u2010diagnosed food allergy, parent\u2010reported eczema and atopic eczema according to UK Working Party criteria, parent\u2010reported ever wheeze, parent\u2010reported physician\u2010diagnosed asthma, and IgE sensitization to food and airborne allergens. Associations between maternal DII scores (continuous and quartiles) and allergic outcomes were assessed using logistic regression, adjusting for maternal age, allergic heredity, farm living, region of birth, siblings, and education.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At age 18\u2009months, 4.9% of children had physician\u2010diagnosed food allergy, 30.6% had eczema, 11.4% had atopic eczema, 15.9% reported ever wheeze, 4.1% had physician\u2010diagnosed asthma, and 19% were IgE sensitized. No significant associations were found between maternal DII scores and the allergic outcomes of interest.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This large birth cohort study found no association between maternal DII during pregnancy and allergic diseases or IgE sensitization in 18\u2010month\u2010old children, suggesting that a proinflammatory diet during pregnancy does not influence early allergic outcomes. Further research is needed to clarify the role of maternal diet in offspring immune development.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pai.70148","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T09:54:53Z","timestamp":1752746093000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Maternal dietary inflammatory index during pregnancy and the risk of offspring allergic disease"],"prefix":"10.1111","volume":"36","author":[{"given":"Jonas","family":"\u00d6sterlund","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Pediatrics Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stina","family":"Bod\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Pediatrics Ume\u00e5 University  Ume\u00e5 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