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We aimed to evaluate associations between pre\u2010pregnancy BMI and GWG with asthma, rhinitis, eczema, food allergy, anaphylaxis, and allergic sensitization during childhood and adolescence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We analyzed 7280 mother\u2013child pairs from Generation XXI, a Portuguese population\u2010based birth cohort. Maternal BMI was categorized per World Health Organization criteria and grouped into underweight\/normal weight vs. overweight\/obesity. GWG was considered using Institute of Medicine (IOM) guidelines and GWG\n                      <jats:italic>z<\/jats:italic>\n                      \u2010scores. Allergic outcomes were assessed via parent\u2010reported physician diagnosis at 4, 7, 10, and 13\u2009years, and allergic sensitization was determined at 10\u2009years using ImmunoCAP. Associations were analyzed using logistic regression models adjusted for confounders.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Children of mothers with excessive GWG had increased odds of asthma at ages 7 and 13 (aOR\u2009=\u20091.30; 95% CI 1.01\u20131.66 and aOR\u2009=\u20091.29; 95% CI 1.01\u20131.65, respectively), and rhinitis at 4 (OR\u2009=\u20091.48; 95% CI 1.10\u20131.98). Higher GWG\n                      <jats:italic>z<\/jats:italic>\n                      \u2010score group was associated with increased odds of asthma (aOR\u2009=\u20091.33; 95% CI 1.03\u20131.72), rhinitis (aOR\u2009=\u20091.54; 95% CI 1.13\u20132.09), and sensitization (aOR\u2009=\u20091.44; 95% CI 1.05\u20131.97). Lower GWG\n                      <jats:italic>z<\/jats:italic>\n                      \u2010score group was associated to higher eczema odds at 13, while higher reduced eczema odds at age 4. Maternal overweight\/obesity was associated with lower odds of eczema at age 13 (aOR\u2009=\u20090.73; 95% CI 0.60\u20130.88). Apart from eczema, maternal BMI showed no significant associations with others allergic diseases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Higher GWG is associated with increased odds of childhood asthma, rhinitis, and sensitization. In contrast, maternal overweight\/obesity is linked to lower odds of eczema, suggesting condition\u2010specific effects of maternal weight on childhood allergy risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pai.70357","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T04:50:58Z","timestamp":1778129458000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Excessive gestational weight gain and risk of asthma, rhinitis and allergic sensitization: Results from a Portuguese birth cohort"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7932-9460","authenticated-orcid":false,"given":"M\u00f3nica","family":"Rodrigues","sequence":"first","affiliation":[{"name":"EPIUnit ITR, Institute of Public Health of the University Porto University of Porto  Porto Portugal"},{"name":"Public Health and Forensic Sciences and Medical Education 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