{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T16:53:00Z","timestamp":1770483180038,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2012,9,29]],"date-time":"2012-09-29T00:00:00Z","timestamp":1348876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Intussusception is the most frequent cause of bowel obstruction in children. Although enema is usually used as the initial treatment, surgery may be required in more than 50% of patients. General anesthesia (<jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content>) has been suggested to increase the rate of enema success. The purpose of this study was to evaluate whether <jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content> increases the success rate of reduction by air enema.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this retrospective single\u2010center study from 1989 to the end of June 2008, patients receiving air enema for intussusception reduction were studied. Multivariable analysis using propensity score was performed to compare the success rate between patients receiving sedation or <jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The success rate of air enema increased from 72% in 1989 to the current rate of 90%. When time elapsed between first symptoms and enema was &gt;12\u00a0h, the success rate decreased significantly (Odds Ratio 0.67 [0.56\u20130.81], <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001). When patients were matched by propensity score, <jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content> significantly increased the likelihood of success (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 5.66 [2.85\u201312.89], <jats:italic>P<\/jats:italic>\u00a0=\u00a00.013).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Air enema performed under <jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content> allows intussusception reduction in more than 90% of patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pan.12035","type":"journal-article","created":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T03:59:29Z","timestamp":1349063969000},"page":"1211-1215","source":"Crossref","is-referenced-by-count":31,"title":["General anesthesia for intussusception reduction by enema"],"prefix":"10.1111","volume":"22","author":[{"given":"Emilien","family":"Purenne","sequence":"first","affiliation":[{"name":"D\u00e9partements d'Anesth\u00e9sie\u2010R\u00e9animation H\u00f4pitaux Universitaires Paris\u2010Sud Assistance Publique \u2013 H\u00f4pitaux de Paris Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phanie","family":"Franchi\u2010Abella","sequence":"additional","affiliation":[{"name":"Radiologie P\u00e9diatrique H\u00f4pitaux Universitaires Paris\u2010Sud Assistance Publique \u2013 H\u00f4pitaux de Paris Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Branchereau","sequence":"additional","affiliation":[{"name":"Chirurgie Pediatrique H\u00f4pitaux Universitaires Paris\u2010Sud Assistance Publique \u2013 H\u00f4pitaux de Paris Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Baujard","sequence":"additional","affiliation":[{"name":"D\u00e9partements d'Anesth\u00e9sie\u2010R\u00e9animation H\u00f4pitaux Universitaires Paris\u2010Sud Assistance Publique \u2013 H\u00f4pitaux de Paris Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Benhamou","sequence":"additional","affiliation":[{"name":"D\u00e9partements d'Anesth\u00e9sie\u2010R\u00e9animation H\u00f4pitaux Universitaires Paris\u2010Sud Assistance Publique \u2013 H\u00f4pitaux de Paris Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Xavier","family":"Mazoit","sequence":"additional","affiliation":[{"name":"D\u00e9partements d'Anesth\u00e9sie\u2010R\u00e9animation H\u00f4pitaux Universitaires Paris\u2010Sud Assistance Publique \u2013 H\u00f4pitaux de Paris Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-0390"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.10.050"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(86)90040-0"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.150.6.1349"},{"key":"e_1_2_8_6_1","unstructured":"The R Foundation for Statistical Computing.Vienna University of Technology Vienna Austria. 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