{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:17:40Z","timestamp":1791001060381,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T00:00:00Z","timestamp":1371168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2013,8]]},"abstract":"Summary<\/jats:title>\n \n Background<\/jats:title>\n \n Inadequate access to oral health care places children at risk of caries. Disease severity and inability to cooperate often result in treatment with general anesthesia (\n GA<\/jats:styled-content>\n ). Sedation is increasingly popular and viewed as lower risk than\n GA<\/jats:styled-content>\n in community settings. Currently, few data are available to quantify pediatric morbidity and mortality related to dental anesthesia.\n <\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n Summarize dental anesthesia\u2010related pediatric deaths described in media reports.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Review of media reports in the\n L<\/jats:styled-content>\n exis\u2010\n N<\/jats:styled-content>\n exis Academic database and a private foundation website.\n Settings<\/jats:italic>\n : Dental offices, ambulatory surgery centers, and hospitals.\n Patients<\/jats:italic>\n :\n US<\/jats:styled-content>\n \u2010based children (\u226421\u00a0years old) who died subsequently receiving anesthesia for a dental procedure between 1980\u20132011.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Most deaths occurred among 2\u20135\u00a0year\u2010olds (\n n<\/jats:italic>\n \u00a0=\u00a021\/44), in an office setting (\n n<\/jats:italic>\n \u00a0=\u00a021\/44), and with a general\/pediatric dentist (\n n<\/jats:italic>\n \u00a0=\u00a025\/44) as the anesthesia provider. In this latter group, 17 of 25 deaths were linked with a sedation anesthetic.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n This series of media reports likely represent only a fraction of the overall morbidity and mortality related to dental anesthesia. These data may indicate an association between mortality and pediatric dental procedures under sedation, particularly in office settings. However, these relationships are difficult to test in the absence of a database that could provide an estimate of incidence and prevalence of morbidity and mortality. With growing numbers of children receiving anesthesia for dental procedures from providers with variable training, it is imperative to be able to track anesthesia\u2010related adverse outcomes. Creating a national database of adverse outcomes will enable future research to advance patient safety and quality.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/pan.12210","type":"journal-article","created":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T02:29:20Z","timestamp":1371176960000},"page":"741-746","source":"Crossref","is-referenced-by-count":138,"title":["Trends in death associated with pediatric dental sedation and general anesthesia"],"prefix":"10.1111","volume":"23","author":[{"given":"Helen H.","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine University of Washington Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Milgrom","sequence":"additional","affiliation":[{"name":"Department of Oral Health Sciences University of Washington Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helene","family":"Starks","sequence":"additional","affiliation":[{"name":"Department of Bioethics and Humanities University of Washington Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wylie","family":"Burke","sequence":"additional","affiliation":[{"name":"Department of Bioethics and Humanities University of Washington Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,14]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"289","article-title":"Project USAP 2000\u2013use of sedative agents by pediatric dentists: a 15\u2010year follow\u2010up survey","volume":"24","author":"Houpt M","year":"2002","journal-title":"Pediatr Dent"},{"key":"e_1_2_8_3_1","first-page":"110","article-title":"Behavior management for the pediatric dental patient","volume":"26","author":"McTigue DJ","year":"2004","journal-title":"Pediatr Dent"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(99)90069-1"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(97)90312-7"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.4.805"},{"key":"e_1_2_8_7_1","first-page":"51","article-title":"Illinois dental anesthesia and sedation survey for 1996","volume":"45","author":"Flick WG","year":"1998","journal-title":"Anesth Prog"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(92)90099-L"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6773.2010.01127.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000086756"},{"key":"e_1_2_8_11_1","first-page":"1","article-title":"Trends in oral health status: United States, 1988\u20131994 and 1999\u20132004","volume":"248","author":"Dye BA","year":"2007","journal-title":"Vital Health Stat 11"},{"key":"e_1_2_8_12_1","first-page":"9","article-title":"Office\u2010based anesthesia: lessons learned from the closed claims project","volume":"65","author":"Domino K","year":"2001","journal-title":"ASA Newsl"}],"container-title":["Pediatric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpan.12210","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pan.12210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T21:00:35Z","timestamp":1696194035000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pan.12210"}},"subtitle":[],"editor":[{"given":"Charles","family":"Cote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,6,14]]},"references-count":11,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/pan.12210"],"URL":"https:\/\/doi.org\/10.1111\/pan.12210","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718028129.793479959","asserted-by":"object"}]},"ISSN":["1155-5645","1460-9592"],"issn-type":[{"value":"1155-5645","type":"print"},{"value":"1460-9592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,14]]}}}