{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T19:56:31Z","timestamp":1762113391892},"reference-count":5,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,6,20]],"date-time":"2013-06-20T00:00:00Z","timestamp":1371686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Aspirin\u2010exacerbated respiratory disease (<jats:styled-content style=\"fixed-case\">AERD<\/jats:styled-content>) has been recognized in adults with chronic asthma. Samter's triad is a subset of <jats:styled-content style=\"fixed-case\">AERD<\/jats:styled-content> where adult patients develop nasal polyps, asthma, and sensitivity to aspirin. This condition is thought not to occur before the third decade of life. We report a 13\u2010year\u2010old boy with nasal polyps who suffered a life\u2010threatening exacerbation of asthma during a graded aspirin challenge. Resuscitation required positive pressure ventilation and inotropic support. Our observations confirm that classical <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>amter's triad can occur in children. We suggest that graded aspirin challenges in children are undertaken in a facility with equipment and staff trained for resuscitation. Consideration should be given to this rare complication when prescribing nonsteroidal anti\u2010inflammatory drugs in the perioperative period. Suspicion of this condition merits referral to an immunologist for desensitization to aspirin.<\/jats:p>","DOI":"10.1111\/pan.12216","type":"journal-article","created":{"date-parts":[[2013,6,20]],"date-time":"2013-06-20T10:50:11Z","timestamp":1371725411000},"page":"757-759","source":"Crossref","is-referenced-by-count":23,"title":["Samter's triad in childhood: a warning for those prescribing <scp>NSAID<\/scp>s"],"prefix":"10.1111","volume":"23","author":[{"given":"Rohan","family":"Ameratunga","sequence":"first","affiliation":[{"name":"Department of Clinical Immunology Auckland City Hospital Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Randall","sequence":"additional","affiliation":[{"name":"Paediatric Intensive Care Unit Starship Children's Hospital Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart","family":"Dalziel","sequence":"additional","affiliation":[{"name":"Emergency Department Starship Children's Hospital Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian J.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Paediatric Intensive Care Unit Starship Children's Hospital Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.328.7437.434"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-68-5-975"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1118"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X0503300218"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2011.02557.x"}],"container-title":["Pediatric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpan.12216","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pan.12216","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T01:00:59Z","timestamp":1696208459000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pan.12216"}},"subtitle":[],"editor":[{"given":"David","family":"Polaner","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2013,6,20]]},"references-count":5,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/pan.12216"],"URL":"https:\/\/doi.org\/10.1111\/pan.12216","archive":["Portico"],"relation":{},"ISSN":["1155-5645","1460-9592"],"issn-type":[{"value":"1155-5645","type":"print"},{"value":"1460-9592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,20]]}}}