{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T14:46:39Z","timestamp":1776350799806,"version":"3.51.2"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,8,24]],"date-time":"2013-08-24T00:00:00Z","timestamp":1377302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Thoracotomy causes severe pain in the postoperative period. Perioperative thoracic paravertebral block reduces pain score and may improve outcome after pediatric cardiac surgery. This prospective study was designed for the efficacy and duration of a single level, single injection ultrasound\u2013guided thoracic paravertebral block (<jats:styled-content style=\"fixed-case\">TPVB<\/jats:styled-content>) for fifteen infants undergoing aortic coarctation repair.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>After approval of the ethical committee and the relatives of the patients, 15 infants who had undergone thoracotomy were enrolled in the study. The patients received 0.5\u00a0ml\u00b7kg<jats:sup>\u22121<\/jats:sup> a bolus 0.25% bupivacaine with epinephrine 1\u00a0:\u00a0200\u00a0000 at T5\u20106 level after standard general anesthesia induction. Anesthesia depth with Index of Consciousness (IOC) and tissue oxygen saturation with cerebral (<jats:styled-content style=\"fixed-case\">rSO<\/jats:styled-content>2\u2010C) and somatic thoracodorsal (<jats:styled-content style=\"fixed-case\">rSO<\/jats:styled-content>2\u2010S) were monitored. Intraoperative hemodynamic and postoperative hemodynamic and pain scores were evaluated for 24\u00a0h after surgery. Face, Legs, Activity, Cry, Consolability (FLACC) score was utilized to measure postoperative pain in the intensive care unit. Rescue 0.05\u00a0mg\u00b7kg<jats:sup>\u22121<\/jats:sup> IV morphine was applied to patients in whom FLACC was &gt;3.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age of the patients was 4.5 (1\u201311) months, and the median intraoperative endtidal isoflurane concentration was 0.6% (0.3\u20130.8). The amount of remifentanil used intraoperatively was 4.5 (2.5\u201314) \u03bcg\u00b7kg<jats:sup>\u2212<\/jats:sup><jats:sup>1<\/jats:sup>\u00b7h<jats:sup>\u22121<\/jats:sup>. Intraoperative heart rate and blood pressure values significantly decreased compared with values detected at 5th, 10th, and 15th min after <jats:styled-content style=\"fixed-case\">TPVB<\/jats:styled-content> application, after incision prior and after cross\u2010clamp (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01). The median time of first dose of morphine application after block was 320 (185\u2013430) min. The median morphine consumption in 24\u00a0h was 0.16 (0.09\u20130.4) mg\u00b7kg<jats:sup>\u22121<\/jats:sup>. The median length of postoperative intensive care unit and in\u2010hospital stay times was 23 (1\u201367) h and 4 (1\u201310) days, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We believe that <jats:styled-content style=\"fixed-case\">TPVB<\/jats:styled-content>, as part of a balanced anesthetic and analgesic regime, provides effective pain relief in patients undergoing aortic coarctation repair.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pan.12252","type":"journal-article","created":{"date-parts":[[2013,8,24]],"date-time":"2013-08-24T05:56:54Z","timestamp":1377323814000},"page":"1078-1083","source":"Crossref","is-referenced-by-count":16,"title":["Anesthesia management with single injection paravertebral block for aorta coarctation in infant"],"prefix":"10.1111","volume":"23","author":[{"given":"Ayda","family":"T\u00fcrk\u00f6z","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Baskent University Istanbul Training and 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Istanbul Training and Medical Research Center Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emre","family":"\u00d6zker","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Baskent University Istanbul Training and Medical Research Center Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u0131za","family":"T\u00fcrk\u00f6z","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Baskent University Istanbul Training and Medical Research Center Istanbul 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