{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T06:15:38Z","timestamp":1696313738568},"reference-count":6,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,9,9]],"date-time":"2014-09-09T00:00:00Z","timestamp":1410220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Children's Hospital of Eastern Ontario"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>We present a case of a 12\u2010year\u2010old male with <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>oeys\u2010<jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ietz syndrome (<jats:styled-content style=\"fixed-case\">LDS<\/jats:styled-content>), a rare life\u2010threatening genetic disorder. Multiple manifestations of <jats:styled-content style=\"fixed-case\">LDS<\/jats:styled-content> were present, including easy bruising, aortic root dilatation, multiple areas of vessel tortuosity, and joint laxity. The patient's medications included a beta\u2010blocker and an angiotensin <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> receptor antagonist for prophylaxis against further aortic root dilatation due to his <jats:styled-content style=\"fixed-case\">LDS<\/jats:styled-content>. He experienced intraoperative hemodynamic instability and became pulseless during an orthopedic procedure, which had to be abandoned. Anesthesia was reattempted 2\u00a0days after cessation of the patient's antihypertensive medications and was successful with only minor postoperative hypertension.<\/jats:p>","DOI":"10.1111\/pan.12511","type":"journal-article","created":{"date-parts":[[2014,9,9]],"date-time":"2014-09-09T12:17:27Z","timestamp":1410265047000},"page":"1302-1304","source":"Crossref","is-referenced-by-count":4,"title":["Hemodynamic instability during anesthesia in an adolescent with <scp>L<\/scp>oeys\u2010<scp>D<\/scp>ietz syndrome: a case report"],"prefix":"10.1111","volume":"24","author":[{"given":"Alexandra C.","family":"Bunting","sequence":"first","affiliation":[{"name":"Faculty of Medicine University of Ottawa Ottawa ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Dylan","family":"Bould","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology The Children's Hospital of Eastern Ontario University of Ottawa Ottawa ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1511"},{"key":"e_1_2_8_3_1","first-page":"114","article-title":"Anesthetic management of a child with Loeys\u2010Dietz syndrome","volume":"20","author":"Postaci A","year":"2012","journal-title":"Anestezi Dergisi"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2007.12.020"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0b013e32833eeb19"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3182768f78"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-199910000-00012"}],"container-title":["Pediatric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpan.12511","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pan.12511","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T11:32:33Z","timestamp":1696246353000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pan.12511"}},"subtitle":[],"editor":[{"given":"David","family":"Polaner","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2014,9,9]]},"references-count":6,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/pan.12511"],"URL":"https:\/\/doi.org\/10.1111\/pan.12511","archive":["Portico"],"relation":{},"ISSN":["1155-5645","1460-9592"],"issn-type":[{"value":"1155-5645","type":"print"},{"value":"1460-9592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,9]]}}}