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Affected individuals are at increased risk of respiratory failure, significant cardiac conduction abnormalities, cardiomyopathy, and sudden cardiac death. In addition, significant skeletal muscle involvement is common, which may lead to contractures, respiratory insufficiency, and airway compromise as the disease progresses. This study is the first report of anesthetic management of a patient with <jats:styled-content style=\"fixed-case\">MFM<\/jats:styled-content>. We report multiple anesthetic encounters of a child with genetically confirmed <jats:styled-content style=\"fixed-case\">BAG<\/jats:styled-content>3\u2010myopathy, a subtype of <jats:styled-content style=\"fixed-case\">MFM<\/jats:styled-content> with severe childhood disease onset. A review of the anesthetic implications of the disease is provided, with specific exploration of possible susceptibility to malignant hyperthermia, rhabdomyolysis, and sensitivity to other anesthetic agents.<\/jats:p>","DOI":"10.1111\/pan.12516","type":"journal-article","created":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T11:00:44Z","timestamp":1410519644000},"page":"231-238","source":"Crossref","is-referenced-by-count":4,"title":["Anesthetic considerations in myofibrillar myopathy"],"prefix":"10.1111","volume":"25","author":[{"given":"Gregory J.","family":"Latham","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine Seattle Children's Hospital University of Washington School of Medicine Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Lopez","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University of Virginia School of Medicine Charlottesville VA 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