{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T05:09:35Z","timestamp":1768453775795,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,2,9]],"date-time":"2016-02-09T00:00:00Z","timestamp":1454976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In patients suffering from epidermolysis bullosa dystrophica (<jats:styled-content style=\"fixed-case\">DEB<\/jats:styled-content>), the most severe form of epidermolysis bullosa, trauma or friction cause separation of the skin from underlying tissue with consecutive painful blisters, scarifications, contractures, and pseudosyndactyly. To retain functionality of the hands surgical procedures are necessary. Anesthesia is challenging as difficult airways make general anesthesia risky. Regional anesthesia is considered controversial in patients with <jats:styled-content style=\"fixed-case\">EB<\/jats:styled-content> as accidental subcutaneous injections can cause severe blisters. As ultrasound\u2010guided procedures became standard of care this might have changed however.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>In this case series, we describe feasibility, efficacy, and safety of ultrasound\u2010guided plexus axillaris block in <jats:styled-content style=\"fixed-case\">DEB<\/jats:styled-content> patients undergoing hand surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We performed a retrospective analysis of the charts of all children with <jats:styled-content style=\"fixed-case\">DEB<\/jats:styled-content> undergoing hand surgery under plexus axillaris block and sedation between 2009 and 2013 in our institution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nineteen procedures in nine children were performed. Induction of anesthesia (securing monitoring, sedation, plexus block) took a mean time of 34 min. Perioperative analgesia was adequate in all procedures. No complications such as airway incidents, conversion to general anesthesia, movement during surgery, incomplete block, or formation of new blisters were seen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Ultrasound\u2010guided plexus axillaris block in <jats:styled-content style=\"fixed-case\">DEB<\/jats:styled-content> patients undergoing hand surgery in our institution has been feasible, effective, and safe.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pan.12860","type":"journal-article","created":{"date-parts":[[2016,2,9]],"date-time":"2016-02-09T08:53:47Z","timestamp":1455008027000},"page":"405-408","source":"Crossref","is-referenced-by-count":8,"title":["Feasibility, efficacy, and safety of ultrasound\u2010guided axillary plexus blockade in pediatric patients with epidermolysis bullosa dystrophica"],"prefix":"10.1111","volume":"26","author":[{"given":"Ingeborg","family":"van den Heuvel","sequence":"first","affiliation":[{"name":"Department of General Pediatrics University Children's Hospital Muenster Muenster Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antje","family":"Gottschalk","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Intensive Care Medicine and Pain Therapy University Hospital Muenster Muenster Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Langer","sequence":"additional","affiliation":[{"name":"Department of Trauma\u2010, Hand\u2010 and Reconstructive Surgery Westfaelische Wilhelms\u2010University Muenster Muenster Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"Hahnenkamp","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University Medicine Greifswald Greifswald Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bj\u00f6rn","family":"Ellger","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Intensive Care Medicine and Pain Therapy University Hospital Muenster Muenster Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2010.01.008"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1267526"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2010.01.011"},{"key":"e_1_2_9_5_1","first-page":"727","article-title":"Anesthetic management in pediatric patients with epidermolysis bullosa: a single center experience","volume":"79","author":"Van Den Heuvel I","year":"2013","journal-title":"Minerva Anestesiol"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/82.5.746"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0b013e32835069c2"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X1003800623"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2011.03780.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2011.09.029"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2011.06805.x"},{"key":"e_1_2_9_12_1","first-page":"CD005487","article-title":"Infraclavicular brachial plexus block for regional anaesthesia of the lower arm","volume":"8","author":"Chin KJ","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.bpo.0000229976.24307.30"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2012.03809.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607113479972"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.06.039"}],"container-title":["Pediatric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpan.12860","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pan.12860","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T15:42:22Z","timestamp":1696261342000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pan.12860"}},"subtitle":[],"editor":[{"given":"Adrian","family":"Bosenberg","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,2,9]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.1111\/pan.12860"],"URL":"https:\/\/doi.org\/10.1111\/pan.12860","archive":["Portico"],"relation":{},"ISSN":["1155-5645","1460-9592"],"issn-type":[{"value":"1155-5645","type":"print"},{"value":"1460-9592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,9]]}}}