{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T14:48:19Z","timestamp":1772722099570,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,2,23]],"date-time":"2016-02-23T00:00:00Z","timestamp":1456185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Temporomandibular joint (<jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content>) ankylosis accompanied by mandibular micrognathia can severely obstruct a patient's upper airway. The obstructive sleep apnea and hypopnea syndrome (<jats:styled-content style=\"fixed-case\">OSAHS<\/jats:styled-content>) resulting from <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> ankylosis and accompanied by mandibular micrognathia, can severely influence the patient's life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to determine if there is a difference in Cormack and Lehane score before and after distraction osteogenesis in such patients, and to evaluate the airway changes and the respiratory outcome using polysomnography after mandibular distraction osteogenesis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This observational prospective study was carried out on 30 <jats:styled-content style=\"fixed-case\">ASA II<\/jats:styled-content> patients with micrognathia and <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> ankylosis undergoing internal distraction osteogenesis. All patients were assessed with polysomnography before surgery and 6 month after surgery. Nasal intubation was done using a fiberoptic bronchoscope, then patients were subjected to the same anesthetic protocol. Direct laryngoscopy was attempted for the Cormack and Lehane grading after induction. The Cormack and Lehane grade was reassessed after facial symmetry was obtained on removal of the distractor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mouth opening and Cormack and Lehane score improved significantly between the initial presentation for placement of mandibular distraction osteogenesis devices and on removal of the destructor under general anesthesia. Polysomnographic studies conducted after distraction confirmed the correction of airway obstruction in all patients: Improvement in Apnea\u2013Hypopnea Index, mean difference (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>), 39.8 (38.8\u201340.9); the number of apneas per hour, mean difference, (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) 41.1 (42.1\u201340.1); and oxygen\u2010desaturation\u2010index mean difference (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) 27.6 (28.3\u201326.8).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Mandibular distraction osteogenesis improved laryngeal view. Distraction osteogenesis can be successfully used for the treatment of obstructive sleep apnea in mandibular hypoplasia patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pan.12869","type":"journal-article","created":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T04:40:51Z","timestamp":1456375251000},"page":"399-404","source":"Crossref","is-referenced-by-count":25,"title":["Improvement in the airway after mandibular distraction osteogenesis surgery in children with temporomandibular joint ankylosis and mandibular hypoplasia"],"prefix":"10.1111","volume":"26","author":[{"given":"Ola","family":"Zanaty","sequence":"first","affiliation":[{"name":"Faculty of Medicine Department of Anesthesia and Surgical Intensive Care University of Alexandria Alexandria Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahira","family":"El Metainy","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Department of Anesthesia and Surgical Intensive Care University of Alexandria Alexandria Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doaa","family":"Abo Alia","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Department of Anesthesia and Surgical Intensive Care University of Alexandria Alexandria Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Medra","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Department of Maxillofacial and Plastic Surgery Alexandria University Alexandria Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,23]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2007.05.004"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.4.437"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.130.3.344"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2009.07.022"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200205000-00005"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000000147"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2014.06.013"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70026-9"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1984.tb08932.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/pan.12049"},{"key":"e_1_2_10_12_1","first-page":"37","article-title":"Mangement of obstructive sleep apnea through distraction osteogenesis of the mandible: a case report","volume":"1","author":"Ravindran C","year":"2006","journal-title":"Sri Ramachandra J Med"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2008.05.058"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1824-7288-38-7"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12663-012-0373-7"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1615\/JLongTermEffMedImplants.v19.i2.50"}],"container-title":["Pediatric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpan.12869","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pan.12869","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T15:42:41Z","timestamp":1696261361000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pan.12869"}},"subtitle":[],"editor":[{"given":"Jerrold","family":"Lerman","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,2,23]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.1111\/pan.12869"],"URL":"https:\/\/doi.org\/10.1111\/pan.12869","archive":["Portico"],"relation":{},"ISSN":["1155-5645","1460-9592"],"issn-type":[{"value":"1155-5645","type":"print"},{"value":"1460-9592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,23]]}}}