{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T12:39:28Z","timestamp":1778503168010,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T00:00:00Z","timestamp":1518393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The use of cuffed vs uncuffed endotracheal tubes in pediatric anesthesia is widely debated. This study aimed to investigate whether the use of cuffed vs uncuffed tubes is associated with an increased incidence of acute postoperative respiratory complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively studied all children aged 0\u20107\u00a0years in which the trachea was intubated between September 28, 2006 and August 26, 2016 in a pediatric university hospital. Logistic regression analysis was performed to estimate the association between tube design (cuffed vs uncuffed) and the incidence of acute postoperative respiratory complications (stridor, wheezing, or dyspnea; desaturations \u226490%) in need of intervention (epinephrine, dexamethasone, nebulizers, supplementary oxygen, or reintubation), adjusting for potential confounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 5247 of 6796 cases (77%), a cuffed tube was used. Acute postoperative respiratory complications in need of intervention occurred in 334 cases (4.9%) and were less common after cuffed than after uncuffed tubes (N\u00a0=\u00a0236, 4.5% vs N\u00a0=\u00a098, 6.3%, respectively, odds ratio 0.70; 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.55\u20100.89). Desaturation occurred less often after cuffed tubes (cuffed: N\u00a0=\u00a01365, 26.0%; uncuffed: N\u00a0=\u00a0512, 33.1%; <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>: 0.71 (0.61\u20100.84)). After adjusting for confounders, there was no difference in acute postoperative respiratory complications between cuffed tubes and uncuffed tubes (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 0.74; 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.55\u20101.01). Subgroup analyses in various age groups did not show significant differences between the use of cuffed or uncuffed tubes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>After adjustment for multiple confounders, the use of cuffed tubes was not associated with an increased incidence of acute respiratory complications in postanesthesia care unit.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pan.13340","type":"journal-article","created":{"date-parts":[[2018,2,13]],"date-time":"2018-02-13T03:40:35Z","timestamp":1518493235000},"page":"210-217","source":"Crossref","is-referenced-by-count":29,"title":["The incidence of postoperative respiratory complications: A retrospective analysis of cuffed vs uncuffed tracheal tubes in children 0\u20107\u00a0years of age"],"prefix":"10.1111","volume":"28","author":[{"given":"Michel","family":"de Wit","sequence":"first","affiliation":[{"name":"Department of Anesthesia Wilhelmina Children's Hospital University Medical Center Utrecht Utrecht University Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda M.","family":"Peelen","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Wilhelmina Children's Hospital University Medical Center Utrecht Utrecht University Utrecht The Netherlands"},{"name":"Department of Epidemiology Julius Center for Health Sciences and Primary Care University Medical Centre Utrecht Utrecht University Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leo","family":"van Wolfswinkel","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Wilhelmina Children's Hospital University Medical Center Utrecht Utrecht University Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2168-7900","authenticated-orcid":false,"given":"Jurgen C.","family":"de Graaff","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Wilhelmina Children's Hospital University Medical Center Utrecht Utrecht University Utrecht The Netherlands"},{"name":"Brain Centre Rudolf Magnus University Medical Centre Utrecht Utrecht University Utrecht The Netherlands"},{"name":"Department of Anesthesia Sophia Children's Hospital Erasmus Medical Center Rotterdam Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,2,12]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Textbook of Pediatric Intensive Care","author":"Rogers MC","year":"1987"},{"key":"e_1_2_7_3_1","first-page":"437","volume-title":"Pediatric Anesthesia","author":"Fisher 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