{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T02:38:53Z","timestamp":1789699133920,"version":"4.0.1"},"reference-count":21,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T00:00:00Z","timestamp":1538524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The decision to proceed with anesthesia and surgery has been controversial in pediatric patients with an upper respiratory tract infection. The <jats:styled-content style=\"fixed-case\">COLDS<\/jats:styled-content> score was proposed by Lee and August as a potential risk stratification scheme, but no validation has been performed on this scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The aim of this study was to evaluate the utility of the <jats:styled-content style=\"fixed-case\">COLDS<\/jats:styled-content> score in predicting perioperative respiratory adverse events and optimize its predictive ability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">COLDS<\/jats:styled-content> scores, incidence of perioperative respiratory adverse events, surgical procedure type, and age were prospectively collected for 536 patients who met inclusion criteria. Area under the receiver operating characteristic curves was computed for total <jats:styled-content style=\"fixed-case\">COLDS<\/jats:styled-content> score and individual <jats:styled-content style=\"fixed-case\">COLDS<\/jats:styled-content> score categories. Multivariable regression was used create an optimized score. To quantify the decrease in risk associated with case cancelation due to illness, the other risk factors in <jats:styled-content style=\"fixed-case\">COLDS<\/jats:styled-content> were assessed separately from upper respiratory infection status and a risk model was created.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The area under the receiver operating characteristic curve for the total <jats:styled-content style=\"fixed-case\">COLDS<\/jats:styled-content> score was 0.69, suggesting that the <jats:styled-content style=\"fixed-case\">COLDS<\/jats:styled-content> score has a moderate predictive ability for perioperative respiratory adverse events. When split into individual component scores, the area under the receiver operating characteristic curve ranged from 0.55 to 0.63. We also found that the area under the receiver operating characteristic curve for the scoring system was higher in younger children than for children aged 4\u20106 (area under receiver operating characteristic curve of 0.70\u20100.71 vs 0.66). The area under the receiver operating characteristic curve for the optimized scoring system was 0.71.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">COLDS<\/jats:styled-content> score has the potential to be a valuable risk assessment tool for prediction of perioperative respiratory adverse events and appears to have a better predictive value in certain subpopulations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pan.13491","type":"journal-article","created":{"date-parts":[[2018,10,5]],"date-time":"2018-10-05T14:09:14Z","timestamp":1538748554000},"page":"1007-1014","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Perioperative respiratory adverse event risk assessment in children with upper respiratory tract infection: Validation of the <scp>COLDS<\/scp> score"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5857-9260","authenticated-orcid":false,"given":"Lisa K.","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine Division of Pediatric Anesthesiology David Geffen School of Medicine University of California Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marsha Kristel L.","family":"Bernardo","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine Division of Pediatric Anesthesiology David Geffen School of Medicine University of California Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan R.","family":"Grogan","sequence":"additional","affiliation":[{"name":"Department of Medicine Statistics Core David Geffen School of Medicine University of California Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Elashoff","sequence":"additional","affiliation":[{"name":"Department of Medicine Statistics Core David Geffen School of Medicine University of California Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy H. P.","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine Division of Pediatric Anesthesiology David Geffen School of Medicine University of California Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0b013e3283534e80"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200108000-00008"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2001.00607.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0952-8180(92)90065-9"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)61193-2"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2006.02059.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31719-6"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2004.01169.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2005.01714.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200303000-00009"},{"key":"e_1_2_9_12_1","first-page":"162","article-title":"Children with respiratory infections \u2013 How and when to perform anesthesia","volume":"49","author":"Becke K","year":"2014","journal-title":"Anaesthesiol Intensivmed Notfallmed Schmerzther"},{"key":"e_1_2_9_13_1","first-page":"Doc04","article-title":"Anesthesia for ORL surgery in children","volume":"13","author":"Becke K","year":"2014","journal-title":"GMS Curr Top Otorhinolaryngol Head Neck Surg"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000268712.00756.dd"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1993.tb07150.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1992.tb02346.x"},{"key":"e_1_2_9_17_1","first-page":"412","article-title":"Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in Europe. Lancet","volume":"5","author":"Habre W","year":"2017","journal-title":"Respir Med"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0000000000000460"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000001216"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/pan.12337"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.594929"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000001895"}],"container-title":["Pediatric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpan.13491","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pan.13491","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T18:40:54Z","timestamp":1694889654000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pan.13491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,3]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1111\/pan.13491"],"URL":"https:\/\/doi.org\/10.1111\/pan.13491","archive":["Portico"],"relation":{},"ISSN":["1155-5645","1460-9592"],"issn-type":[{"value":"1155-5645","type":"print"},{"value":"1460-9592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,3]]},"assertion":[{"value":"2017-11-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}