{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T15:46:42Z","timestamp":1759938402296,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T00:00:00Z","timestamp":1565568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003747","name":"Department of Health, State Government of Victoria","doi-asserted-by":"publisher","award":["Victorian Government Operational Infrastructure Su"],"award-info":[{"award-number":["Victorian Government Operational Infrastructure Su"]}],"id":[{"id":"10.13039\/501100003747","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["Grant ID 1053889"],"award-info":[{"award-number":["Grant ID 1053889"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Tight control of tidal volume using accurate monitoring may improve neonatal outcomes. However, respiratory function monitors incorporated in current anesthetic workstations are generally inaccurate at tidal volumes used for infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To determine if a specific respiratory function monitor for neonatal infants improved expired tidal volume delivery during anesthesia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Infants &lt;3\u00a0months old requiring intubation for surgery in the operating theater were studied. After intubation a Phillips NM3, Acutronic Florian, or Novametrix Ventcheck Respiratory Function Monitor was integrated into the circuit, and clinicians given access to the display for the duration of anesthesia. Breath\u2010to\u2010breath expired tidal volume delivery, leak, and delivered pressure were recorded, with cardiorespiratory parameters. These were compared with a matched control group with clinicians blinded to respiratory function monitor display.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 10\u00a0055 and 2569 inflations were measured in the respiratory function monitor visible (n\u00a0=\u00a032) and masked (n\u00a0=\u00a033) groups, respectively, with mean (standard deviation) delivered expired tidal volume 7.5 (2.4)\u00a0mL\/kg and 7.7 (3.0)\u00a0mL\/kg, respectively; mean difference (95% confidence interval) \u22120.2 (\u22121.1, 0.8)\u00a0mL\/kg (Welch's <jats:italic>t<\/jats:italic> test). In the visible group, 55.6% of expired tidal volumes were between 4 and 8\u00a0mL\/kg compared to 51.7% in the masked group; relative benefit (95% confidence interval), 1.08 (1.03, 1.12). Expired tidal volume was less likely to be &lt;4\u00a0mL\/kg in the visible group compared to masked group; 6.4% vs 9.8%, 1.53 (1.33, 1.76). The use of a respiratory function monitor also reduced the number of inflations &gt;10\u00a0mL\/kg; 13.0% vs 22.0%, 1.11 (1.09, 1.14).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Tidal volumes &lt;4\u00a0mL\/kg and &gt;10\u00a0mL\/kg are frequently delivered during neonatal anesthesia. The inclusion of an accurate respiratory function monitor may reduce the risk of exposure to potentially harmful tidal volumes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pan.13707","type":"journal-article","created":{"date-parts":[[2019,7,18]],"date-time":"2019-07-18T15:08:56Z","timestamp":1563462536000},"page":"920-926","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A dedicated respiratory function monitor to improve tidal volume delivery during neonatal anesthesia"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1522-4691","authenticated-orcid":false,"given":"William K.","family":"Atkins","sequence":"first","affiliation":[{"name":"Neonatal Research Murdoch Children\u2019s Research Institute Parkville Vic. Australia"},{"name":"Department of Paediatrics University of Melbourne Parkville Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2237-7231","authenticated-orcid":false,"given":"Rob","family":"McDougall","sequence":"additional","affiliation":[{"name":"Neonatal Research Murdoch Children\u2019s Research Institute Parkville Vic. Australia"},{"name":"Department of Paediatrics University of Melbourne Parkville Vic. Australia"},{"name":"Department of Anaesthesia The Royal Children's Hospital Parkville Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth J.","family":"Perkins","sequence":"additional","affiliation":[{"name":"Neonatal Research Murdoch Children\u2019s Research Institute Parkville Vic. Australia"},{"name":"Department of Neonatology The Royal Children's Hospital Parkville Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prue M.","family":"Pereira\u2010Fantini","sequence":"additional","affiliation":[{"name":"Neonatal Research Murdoch Children\u2019s Research Institute Parkville Vic. Australia"},{"name":"Department of Paediatrics University of Melbourne Parkville Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David G.","family":"Tingay","sequence":"additional","affiliation":[{"name":"Neonatal Research Murdoch Children\u2019s Research Institute Parkville Vic. Australia"},{"name":"Department of Paediatrics University of Melbourne Parkville Vic. Australia"},{"name":"Department of Neonatology The Royal Children's Hospital Parkville Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1007\/978-3-642-01219-8","volume-title":"Pediatric and neonatal mechanical ventilation","author":"Rimensberger P","year":"2015"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2008.08.016"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2008.49"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1996.80.5.1485"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01709236"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2011-301041"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2005.082271"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2017-312640"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000326080"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2009.165878"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2011.09.017"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2004.058685"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.01.074"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3181cfc416"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000149854.61192.DC"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31829102de"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00188282"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198104000-00007"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2007.120097"}],"container-title":["Pediatric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpan.13707","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pan.13707","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pan.13707","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pan.13707","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T07:42:38Z","timestamp":1694072558000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pan.13707"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,12]]},"references-count":19,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1111\/pan.13707"],"URL":"https:\/\/doi.org\/10.1111\/pan.13707","archive":["Portico"],"relation":{},"ISSN":["1155-5645","1460-9592"],"issn-type":[{"type":"print","value":"1155-5645"},{"type":"electronic","value":"1460-9592"}],"subject":[],"published":{"date-parts":[[2019,8,12]]},"assertion":[{"value":"2018-09-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}