{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:36:34Z","timestamp":1777613794175,"version":"3.51.4"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,11,29]],"date-time":"2020-11-29T00:00:00Z","timestamp":1606608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Blood product utilization in injured children is poorly characterized; the decision to prepare products or transfuse patients can be difficult due to a lack of reliable evidence of transfusion needs across pediatric age\u2010groups and injury types. We conducted an audit of transfusion practices in pediatric trauma based on age, injuries, and mechanism of injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed and cross\u2010referenced blood product transfusion practice data from the trauma registry and the anesthesia transfusion record database at a level 1 pediatric trauma center over a 10\u2010year period. Demographic data, injury severity scores, and survival statistics were obtained from the trauma registry. Transfusion rates are reported separately for hospital admission and for intraoperative transfusions for procedures performed during the first two hospital days. Descriptive statistical analysis was used to compare specific groups based on age, injury type, and mechanism of injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We report 14\u00a0569 trauma admissions of 14\u00a0606 patients. The transfusion rate during the admission was 1.56% (227\/14\u00a0569). 4591 (30.9%) admissions had surgical interventions in first two days of hospitalization with an intraoperative transfusion rate of 2.98%. Patients younger than one year had the highest transfusion rate during admission (2.8%), and the highest transfusion rate during surgical procedures performed in the first two days of the admission (18.87%). Admissions due to vascular injuries had the highest transfusion rates in infancy followed by hollow visceral injuries in adolescents (71.4% and 25%, respectively). Vascular injuries in most age\u2010groups also had high transfusion rates ranging from 11% in 5\u2010 to 9\u2010year age\u2010group to 71% in infants. Mechanisms with the highest transfusion rates were firearm wounds in patients older than one year and vehicular accidents for patients younger than one year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The overall blood product needs in the pediatric trauma population are low (1.56%). Selected populations requiring higher rates of need include infants younger than one year, and children with thoracic and vascular injuries. Understanding transfusion patterns is important to optimize resource allocation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pan.14077","type":"journal-article","created":{"date-parts":[[2020,11,15]],"date-time":"2020-11-15T17:15:17Z","timestamp":1605460517000},"page":"186-196","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Audit of blood product utilization in the care of injured children"],"prefix":"10.1111","volume":"31","author":[{"given":"Patrick E.","family":"McGovern","sequence":"first","affiliation":[{"name":"Division of Pediatric General Thoracic and Fetal Surgery The Children\u2019s Hospital of Philadelphia Philadelphia PA USA"},{"name":"Department of Surgery Temple University Hospital Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2581-4716","authenticated-orcid":false,"given":"Lezhou","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Biomedical &amp; Health Informatics The Children\u2019s Hospital of Philadelphia Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sieta","family":"Rao","sequence":"additional","affiliation":[{"name":"Division of Pediatric General Thoracic and Fetal Surgery The Children\u2019s Hospital of Philadelphia Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Ahumada","sequence":"additional","affiliation":[{"name":"Predictive Analytics Johns Hopkins All Children\u2019s Hospital St. Petersburg FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7422-6676","authenticated-orcid":false,"given":"David F.","family":"Friedman","sequence":"additional","affiliation":[{"name":"Blood Bank and Transfusion Medicine Division The Children\u2019s Hospital of Philadelphia Philadelphia PA USA"},{"name":"Department of Pediatrics University of Pennsylvania Perelman School of Medicine Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael L.","family":"Nance","sequence":"additional","affiliation":[{"name":"Division of Pediatric General Thoracic and Fetal Surgery The Children\u2019s Hospital of Philadelphia Philadelphia PA USA"},{"name":"Department of Surgery University of Pennsylvania Perelman School of Medicine Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7145-4921","authenticated-orcid":false,"given":"Jorge A.","family":"G\u00e1lvez","sequence":"additional","affiliation":[{"name":"Department of Biomedical &amp; Health Informatics The Children\u2019s Hospital of Philadelphia Philadelphia PA USA"},{"name":"Department of Anesthesiology &amp; Critical Care Medicine The Children\u2019s Hospital of Philadelphia Philadelphia PA USA"},{"name":"Department of Anesthesiology &amp; Critical Care University of Pennsylvania Perelman School of Medicine Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,11,29]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2019.11.041"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13857"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(89)80237-4"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000001823"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2016.09.039"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2004.01549.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03568.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2014.07.013"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/amiajnl-2013-002241"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000002432"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/pq9.0000000000000165"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.12"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e3181ba7074"},{"key":"e_1_2_10_15_1","article-title":"Machine learning applied to registry data: development of a patient\u2010specific prediction model for blood transfusion requirements during craniofacial surgery using the pediatric craniofacial perioperative registry dataset","author":"Jalali A","year":"2020","journal-title":"Anesth Analg"}],"container-title":["Pediatric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pan.14077","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pan.14077","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pan.14077","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T06:41:28Z","timestamp":1693636888000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pan.14077"}},"subtitle":[],"editor":[{"given":"Susan","family":"Goobie","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,11,29]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1111\/pan.14077"],"URL":"https:\/\/doi.org\/10.1111\/pan.14077","archive":["Portico"],"relation":{},"ISSN":["1155-5645","1460-9592"],"issn-type":[{"value":"1155-5645","type":"print"},{"value":"1460-9592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,29]]},"assertion":[{"value":"2020-06-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}