{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T15:58:51Z","timestamp":1776959931177,"version":"3.51.4"},"reference-count":47,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,6,29]],"date-time":"2023-06-29T00:00:00Z","timestamp":1687996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Bleeding and transfusion remain important concerns during surgical correction of scoliosis even when multiple conservative strategies, such as preoperative recombinant erythropoietin and\/or antifibrinolytic agents, are used. The current work aimed to determine the impact of other potential risk factors, especially the volume of intraoperative fluid intake, on the perioperative risk of allogenic transfusion during surgical correction of adolescent idiopathic scoliosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective study included all cases of adolescent idiopathic scoliosis operated in a single center during 2\u2009years (2018\u20132020). Predictors analyzed were as follows: body mass index, preoperative hemoglobin concentration, thoracoplasty, preoperative halo\u2010gravity, volume of intraoperative crystalloid administration, use of esophageal Doppler (for goal\u2010directed fluid therapy), and duration of surgery. Statistical analyses were performed using a multivariable logistic regression model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred patients were included in the analysis. Multivariable analysis found: an increased volume of intraoperative crystalloid administration as a significant predictor of allogenic blood transfusion. Receiving operator characteristics analysis found the model exhibiting an area under the curve of 0.85 (95% confidence interval: 0.75\u20130.95). Optimizing stroke volume using esophageal Doppler was associated with a decrease in intraoperative crystalloid intake.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These results indicate a statistical association between the increase in crystalloid intake and the risk of allogenic blood transfusion during surgical correction of adolescent idiopathic scoliosis. Controlled studies are needed to address the causative relation between intraoperative fluid intake and the risk of allogenic transfusion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pan.14722","type":"journal-article","created":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T06:28:05Z","timestamp":1688106485000},"page":"829-836","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The association between intraoperative fluid management and perioperative allogenic blood transfusion during adolescent idiopathic scoliosis surgery"],"prefix":"10.1111","volume":"33","author":[{"given":"Pierre","family":"Pardessus","sequence":"first","affiliation":[{"name":"Universit\u00e9 de Paris\u2010Cit\u00e9  Paris France"},{"name":"Department of Anesthesia and Intensive Care Robert Debr\u00e9 Hospital  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maud","family":"Loiselle","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris\u2010Cit\u00e9  Paris France"},{"name":"Department of Anesthesia and Intensive Care Robert Debr\u00e9 Hospital  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vilnis","family":"Silins","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris\u2010Cit\u00e9  Paris France"},{"name":"Department of Anesthesia and Intensive Care Robert Debr\u00e9 Hospital  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne\u2010Laure","family":"Horlin","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris\u2010Cit\u00e9  Paris France"},{"name":"Department of Anesthesia and Intensive Care Robert Debr\u00e9 Hospital  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly","family":"Brouns","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris\u2010Cit\u00e9  Paris France"},{"name":"Department of Anesthesia and Intensive Care Robert Debr\u00e9 Hospital  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucile","family":"Marsac","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris\u2010Cit\u00e9  Paris France"},{"name":"Department of Anesthesia and Intensive Care Robert Debr\u00e9 Hospital  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Fait","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris\u2010Cit\u00e9  Paris France"},{"name":"Department of Anesthesia and Intensive Care Robert Debr\u00e9 Hospital  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brice","family":"Ilharreborde","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris\u2010Cit\u00e9  Paris France"},{"name":"FHU I2D2. 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