{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T09:10:19Z","timestamp":1733735419543,"version":"3.30.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T00:00:00Z","timestamp":1728259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Neonates are relatively prone to immediate, early, and late complications related to central venous cannulation (CVC). Ultrasound\u2010guided brachiocephalic vein (BCV) cannulation has proven to be safe in neonates. Although studies addressed the immediate and early complications of CVC via BCV in neonates, few explored long\u2010term maintenance\u2010related complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To evaluate the incidences of long\u2010term maintenance\u2010related complications including central line\u2010associated blood stream infection (CLABSI), central line\u2010associated thrombosis (CLAT), and mechanical complications (CLAMC) of nontunneled BCV cannulation in neonates and their relationship with patient and catheter\u2010related factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study included BCV cannulations of neonates with postconceptional age of \u226444\u2009weeks performed between January 2018 and January 2023. The incidences of complications were determined. Correlations between complications and postconceptional age, body weight, indication for catheter placement, the size and side of the catheter, as well as catheter dwell time were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 89 BCV cannulations performed in 71 neonates. The incidences were 19.3 [95%CI: 12.88\u201328.76] total complications, 5.9 [95%CI: 2.84\u201312.06] CLABSI, 3.4 [95%CI: 1.30\u20138.58] CLAT and 10.1 [95%CI: 5.76\u201317.49] CLAMC in 1000 catheter days. There were 23 (25.8%) total complications; 7 (7.9%) were CLABSI, 4 (4.5%) were CLAT, and 12 (13.5%) were CLAMC. The multivariate analysis revealed that prolonged dwell time was associated with high incidence of total complications [OR: 1.07, 95% CI: 1.00\u20131.14, <jats:italic>p<\/jats:italic>\u2009=\u2009.047] and the catheter of smaller size (3F in this study) was associated with higher incidence of CLABSI [OR: 8.91, 95% CI: 1.03\u201377.45, <jats:italic>p<\/jats:italic>\u2009=\u2009.047].<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this study, the prolonged dwell time and smaller sized catheter was found to be independent predictors of total complications and CLABSI, respectively. The independent predictive effects of postconceptional age and body weight should be addressed in larger studies as potential risk factors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pan.15018","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T09:45:17Z","timestamp":1728294317000},"page":"39-46","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010term maintenance\u2010related complications of brachiocephalic vein cannulations in neonates: A retrospective evaluation"],"prefix":"10.1111","volume":"35","author":[{"given":"Eser","family":"Simsek","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology and Reanimation Hacettepe University School of Medicine  Ankara 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