{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T08:55:13Z","timestamp":1767862513623,"version":"3.49.0"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Congenital long QT syndrome (LQTS) and Catecholaminergic Polymorphic ventricular Tachycardia (CPVT) are inherited arrhythmogenic disorders leading to an increased risk of life\u2010threatening arrhythmias. Left cardiac sympathetic denervation (LCSD), currently performed by video\u2010assisted thoracoscopic surgery (VATS) is a well\u2010established treatment for patients not fully protected by drugs. Peri\u2010operative pain management represents a challenge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To assess the impact of a multimodal approach for perioperative pain management including combined regional anesthesia on postoperative pain scores, opioid requirements and neuropathic pain incidence in pediatric LQTS and CPVT patients undergoing VATS\u2010LCSD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted on consecutive children undergoing VATS\u2010LCSD at a single center from 2021 to March 2025. Per protocol, they all received Erector Spinae Plane (ESP) and Serratus Plane (SP) block. A perifascial catheter was placed following ESP for continuous local anesthetic infusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>15 patients were enrolled (median age 6.9\u2009years, IQR 4.3\u20139.8, median weight 24\u2009kg, IQR 18.3\u201335.5). Most (13, 87%) had LQTS and almost one third had a high\u2010risk genotype. There were no major complications. There was only 1 case (7%) of accidental removal of the ESP catheter, in whom prophylactic morphine was used. Pain scores, as assessed by VAS, were below 2 in all patients; none needed additional doses of opioids nor ketorolac or developed neuropathic pain postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results support the use of a combined regional anesthesia protocol for peri\u2010operative pain management in pediatric channelopathy patients undergoing VATS\u2010LCSD. This approach may improve overall quality of care for this vulnerable population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pan.70075","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:06:15Z","timestamp":1762430775000},"page":"173-180","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Optimizing Peri\u2010Operative Pain Management in Children With Long\n                    <scp>QT<\/scp>\n                    Syndrome and Catecholaminergic Polymorphic Ventricular Tachycardia Undergoing Left Cardiac Sympathetic Denervation: A Case Series on Continuous Erector Spinae Plane Block and Serratus Plane Block"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7862-4863","authenticated-orcid":false,"given":"V.","family":"Mossetti","sequence":"first","affiliation":[{"name":"Anesthesia and Intensive Care Regina Margherita Children Hospital, Citt\u00e0 Della Salute e Della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Di Corrado","sequence":"additional","affiliation":[{"name":"Anesthesia and Intensive Care Regina Margherita Children Hospital, Citt\u00e0 Della Salute e Della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"HaxhiNasto","sequence":"additional","affiliation":[{"name":"Anesthesia and Intensive Care Regina Margherita Children Hospital, Citt\u00e0 Della Salute e Della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Maiolo","sequence":"additional","affiliation":[{"name":"Anesthesia and Intensive Care Regina Margherita Children Hospital, Citt\u00e0 Della Salute e Della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sciurti","sequence":"additional","affiliation":[{"name":"Anesthesia and Intensive Care Regina Margherita Children Hospital, Citt\u00e0 Della Salute e Della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Quaglia","sequence":"additional","affiliation":[{"name":"Anesthesia and Intensive Care Regina Margherita Children Hospital, Citt\u00e0 Della Salute e Della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Papagiannis","sequence":"additional","affiliation":[{"name":"Department of Paediatric Cardiology and Adult Congenital Heart Disease Onassis Cardiac Surgery Centre  Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Dagradi","sequence":"additional","affiliation":[{"name":"Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Istituto Auxologico Italiano, IRCCS  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Crotti","sequence":"additional","affiliation":[{"name":"Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Istituto Auxologico Italiano, IRCCS  Milan Italy"},{"name":"Department of Medicine and Surgery University of Milano\u2010Bicocca  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Cerrina","sequence":"additional","affiliation":[{"name":"Surgical Department Regina Margherita Children Hospital, Citt\u00e0 Della Salute e Della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Gennari","sequence":"additional","affiliation":[{"name":"Surgical Department Regina Margherita Children Hospital, Citt\u00e0 Della Salute e Della Scienza  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Pugliese","sequence":"additional","affiliation":[{"name":"Department of Surgery Fondazione IRCCS Policlinico San Matteo  Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Guerrera","sequence":"additional","affiliation":[{"name":"Department of Cardio\u2010Thoracic and Vascular Surgery Citt\u00e0 Della Salute e Della Scienza  Turin Italy"},{"name":"Department of Surgical Sciences University of Turin  Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. 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