{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:31:24Z","timestamp":1791318684043,"version":"4.3.1"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,10,24]],"date-time":"2013-10-24T00:00:00Z","timestamp":1382572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The objective of this study was to determine the efficacy of percutaneous radiofrequency (<jats:styled-content style=\"fixed-case\">RF<\/jats:styled-content>) treatment of the trigeminal ganglion for treating patients with trigeminal neuralgia, to determine which patients have a long\u2010term benefit, and to evaluate the effect of <jats:styled-content style=\"fixed-case\">RF<\/jats:styled-content> parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study in 28 consecutive patients in combination with a follow\u2010up questionnaire (<jats:italic>n<\/jats:italic>\u00a0=\u00a026, 93% response).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>An initial treatment effect of 89% was observed, 60% sustained at 12\u2010month follow\u2010up. Major side effects were hypesthesia (56%), dry eye (20%), and masseter muscle weakness (12%). A lower sensory stimulation threshold during treatment was associated with better patient satisfaction (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.016), improved pain relief (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.039), and trended toward more hypesthesia (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.077).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>This low\u2010volume study reported treatment effects in an older population that were similar to previous studies. Only a higher incidence of hypesthesia was detected by long\u2010term follow\u2010up. This study supported the high efficiency of <jats:styled-content style=\"fixed-case\">RF<\/jats:styled-content> treatment, but there was a high level of side effects. Most notable, low sensory stimulation was associated with increased hypesthesia, whereas higher stimulation levels yielded less effectiveness. Further investigation of an optimal sensory stimulation range for percutaneous <jats:styled-content style=\"fixed-case\">RF<\/jats:styled-content> treatment of the trigeminal ganglion was found to be warranted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/papr.12124","type":"journal-article","created":{"date-parts":[[2013,10,24]],"date-time":"2013-10-24T05:02:37Z","timestamp":1382590957000},"page":"581-587","source":"Crossref","is-referenced-by-count":18,"title":["Relationship between Sensory Stimulation and Side Effects in Percutaneous Radiofrequency Treatment of the Trigeminal Ganglion"],"prefix":"10.1111","volume":"14","author":[{"given":"Mark V.","family":"Koning","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Erasmus University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick J.","family":"Koning","sequence":"additional","affiliation":[{"name":"Departments of Anesthesiology and Cardiothoracic Surgery Institute for Cardiovascular Research VU University Medical Center Amsterdam The Netherlands"},{"name":"Department of Integrated Neurovascular Biology INSERM U1083 CNRS UMR 6214 LUNAM University Universit\u00e9 d'Angers Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henk M.","family":"Koning","sequence":"additional","affiliation":[{"name":"Department of Pain Therapy Medical Center Jan van Goyen Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten","family":"van Kleef","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Management Maastricht University Medical Center Maastricht The Netherlands"},{"name":"Department of Anesthesiology and Pain Management VU University Medical Center Amsterdam The 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