{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T17:07:30Z","timestamp":1780938450656,"version":"3.54.1"},"reference-count":49,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,11,20]],"date-time":"2013-11-20T00:00:00Z","timestamp":1384905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"This study was financially supported by the Covenant between University of Groningen and Hanze University of Applied Sciences Groningen, the Netherlands. The study was part of the Dissertation Miriam van Ittersum at the University of Groningen, the Netherlands (September 2010), entitled \u00ef\u00bf\u00bdChronic musculoskeletal disorders: assessment and intervention\u00ef\u00bf\u00bd, ISBN 978 94 6070 021 7; chapter 7, pp. 134 - 154. The full dissertation is available at http:\/\/www.hanze.nl\/NR\/rdonlyres\/94D24B9C-4F74-45C6-B726-FAC97D03C265\/0\/MiriamvanIttersumProefschrift.pdf"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mounting evidence supports the use of face\u2010to\u2010face pain neuroscience education for the treatment of chronic pain patients. This study aimed at examining whether written education about pain neuroscience improves illness perceptions, catastrophizing, and health status in patients with fibromyalgia.<\/jats:p><jats:p>A double\u2010blind, multicenter randomized controlled clinical trial with 6\u2010month follow\u2010up was conducted. Patients with <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a0114) that consented to participate were randomly allocated to receive either written pain neuroscience education or written relaxation training. Written pain neuroscience education comprised of a booklet with pain neuroscience education plus a telephone call to clarify any difficulties; the relaxation group received a booklet with relaxation education and a telephone call. The revised illness perception questionnaire, Pain Catastrophizing Scale, and fibromyalgia impact questionnaire were used as outcome measures. Both patients and assessors were blinded. Repeated\u2010measures analyses with last observation carried forward principle were performed. Cohen's <jats:italic>d<\/jats:italic> effect sizes (<jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>) were calculated for all within\u2010group changes and between\u2010group differences.<\/jats:p><jats:p>The results reveal that written pain neuroscience education does not change the impact of <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content> on daily life, catastrophizing, or perceived symptoms of patients with <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content>. Compared with written relaxation training, written pain neuroscience education improved beliefs in a chronic timeline of <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.03; <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\u00a0=\u00a00.50), but it does not impact upon other domains of illness perceptions.<\/jats:p><jats:p>Compared with written relaxation training, written pain neuroscience education slightly improved illness perceptions of patients with <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content>, but it did not impart clinically meaningful effects on pain, catastrophizing, or the impact of <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content> on daily life. Face\u2010to\u2010face sessions of pain neuroscience education are required to change inappropriate cognitions and perceived health in patients with <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/papr.12137","type":"journal-article","created":{"date-parts":[[2013,11,20]],"date-time":"2013-11-20T11:24:26Z","timestamp":1384946666000},"page":"689-700","source":"Crossref","is-referenced-by-count":68,"title":["Written Pain Neuroscience Education in Fibromyalgia: A Multicenter Randomized Controlled Trial"],"prefix":"10.1111","volume":"14","author":[{"given":"Miriam W.","family":"van Ittersum","sequence":"first","affiliation":[{"name":"Research and Innovation Group in Health Care and in Nursing Hanze University of Applied Sciences Groningen Groningen The Netherlands"},{"name":"Department of Health Sciences, Community and Occupational Medicine University Medical Centre Groningen University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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