{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T08:03:21Z","timestamp":1767773001169},"reference-count":24,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,4,21]],"date-time":"2014-04-21T00:00:00Z","timestamp":1398038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Measuring <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> is simple, inexpensive, permits the health status to be measured over time, and is useful to compare or initiate treatments and evaluate results, facilitating homogenization in patient inclusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate disease\u2010specific and generic <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> and influence of associated factors in patients undergoing open debridement for acute postsurgical knee prosthetic joint infection after <jats:styled-content style=\"fixed-case\">TKR<\/jats:styled-content> at 12 and 48\u00a0months after completing antibiotic treatment and considered cured of infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Health\u2010related quality\u2010of\u2010life measures were administered at baseline (<jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content>) and 12 and 48\u00a0months (<jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036) in patients with prosthesis retention, no symptoms of infection, and <jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content> (\u2264\u00a01\u00a0mg\/dL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty patients were included, and 24 were evaluated at 48\u00a0months. <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> scores improved significantly (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01) at 12 and 48\u00a0months. The effect size was 0.72 for stiffness, 2.01 for pain, and 2.15 for function. At 48\u00a0months, improvements were greater (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.02) except for stiffness. The most frequently isolated microorganisms were <jats:italic>Staphylococcus aureus<\/jats:italic> (14 patients) and coagulase\u2010negative staphylococci (9 patients). <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036 physical role, bodily pain, emotional role, and mental health dimension scores at 12 and 48\u00a0months were significantly worse in patients with isolates of <jats:italic>Staphylococcus aureus<\/jats:italic> (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Health\u2010related quality\u2010of\u2010life measures detected significant differences in outcomes in patients infected by <jats:italic>S. aureus<\/jats:italic> compared with patients infected by other microorganisms. <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> measures may provide useful complementary information on outcomes after acute postoperative infection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/papr.12214","type":"journal-article","created":{"date-parts":[[2014,4,21]],"date-time":"2014-04-21T07:33:30Z","timestamp":1398065610000},"page":"610-617","source":"Crossref","is-referenced-by-count":7,"title":["Measuring Outcomes: Pain and Quality of Life 48\u00a0Months After Acute Postoperative Total Knee Prosthetic Joint Infection"],"prefix":"10.1111","volume":"15","author":[{"given":"Montserrat","family":"N\u00fa\u00f1ez","sequence":"first","affiliation":[{"name":"Rheumatology Department Biomedical Research Institute August Pi i Sunyer (IDIBAPS) Hospital Cl\u00ednic Universitari Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Vilchez Cavazos","sequence":"additional","affiliation":[{"name":"Orthopedic Surgery Department Hospital Cl\u00ednic Universitari Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"N\u00fa\u00f1ez 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