{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T03:20:09Z","timestamp":1768879209344,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,6,23]],"date-time":"2014-06-23T00:00:00Z","timestamp":1403481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Beijing Municipal Science & Technology Commission","award":["Z131107002213061"],"award-info":[{"award-number":["Z131107002213061"]}]},{"name":"The Excellent Medical Staff of Beijing","award":["2011-3-034"],"award-info":[{"award-number":["2011-3-034"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Although pulsed radiofrequency treatment (<jats:styled-content style=\"fixed-case\">PRFT<\/jats:styled-content>) has been used to treat trigeminal neuralgia (<jats:styled-content style=\"fixed-case\">TN<\/jats:styled-content>) safely, satisfactory improvement is lacking. Recently, much attention has been paid to the <jats:styled-content style=\"fixed-case\">PRFT<\/jats:styled-content> dose and intra\u2010operative parameters. It has been reported that high\u2010voltage <jats:styled-content style=\"fixed-case\">PRFT<\/jats:styled-content> could significantly reduce discogenic pain. However, there is no study investigating the effects of high\u2010voltage <jats:styled-content style=\"fixed-case\">PRFT<\/jats:styled-content> on <jats:styled-content style=\"fixed-case\">TN<\/jats:styled-content>. The aim of this prospective, randomized, double\u2010blinded study was to evaluate the efficacy and safety of high\u2010voltage <jats:styled-content style=\"fixed-case\">PRFT<\/jats:styled-content> in comparison with standard\u2010voltage <jats:styled-content style=\"fixed-case\">PRFT<\/jats:styled-content> for idiopathic <jats:styled-content style=\"fixed-case\">TN<\/jats:styled-content>. Sixty severe <jats:styled-content style=\"fixed-case\">TN<\/jats:styled-content> patients were randomly assigned to 2 groups treated with <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\u2010guided standard\u2010 or high\u2010voltage\u2010pulsed radiofrequency (<jats:styled-content style=\"fixed-case\">RF<\/jats:styled-content>) of Gasserian ganglion, respectively, between <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2012 and <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>uly 2012. Numeric Rating Scales (<jats:styled-content style=\"fixed-case\">NRS<\/jats:styled-content>), carbamazepine dose, and side effects were evaluated at day 1, weeks 1 and 2, months 1, 3, and 6, and 1\u00a0year postoperative. There were 27 patients in the standard\u2010voltage group and 26 patients in the high\u2010voltage group who completed the 1\u2010year follow\u2010up study. The effective rates in the standard\u2010voltage and high\u2010voltage <jats:styled-content style=\"fixed-case\">PRFT<\/jats:styled-content> groups were 41% and 69%, respectively, at 1, 3, and 6\u00a0months postoperative (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.037). The effective rate in the standard\u2010voltage group decreased to 19% at 1\u2010year postoperative, while in the high\u2010voltage group remained at 69% (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.000). No significant side effects were detected in both groups. In conclusion, <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\u2010guided high\u2010voltage <jats:styled-content style=\"fixed-case\">PRFT<\/jats:styled-content> is an effective and safe interventional therapeutic choice for idiopathic <jats:styled-content style=\"fixed-case\">TN<\/jats:styled-content> patients.<\/jats:p>","DOI":"10.1111\/papr.12227","type":"journal-article","created":{"date-parts":[[2014,6,23]],"date-time":"2014-06-23T15:08:49Z","timestamp":1403536129000},"page":"595-603","source":"Crossref","is-referenced-by-count":50,"title":["Comparison of High\u2010voltage\u2010 with Standard\u2010voltage Pulsed Radiofrequency of Gasserian Ganglion in the Treatment of Idiopathic Trigeminal Neuralgia"],"prefix":"10.1111","volume":"15","author":[{"given":"Luo","family":"Fang","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Pain Management Beijing Tiantan Hospital Capital Medical University Beijing 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