{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:47:38Z","timestamp":1792806458290,"version":"4.5.0"},"reference-count":46,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,2,25]],"date-time":"2017-02-25T00:00:00Z","timestamp":1487980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Varicella zoster virus reactivation can cause permanent histological changes in the central and peripheral nervous system. Neural inflammatory changes or damage to the dorsal root ganglia sensory nerve fibers during reactivation can lead to postherpetic neuralgia (<jats:styled-content style=\"fixed-case\">PHN<\/jats:styled-content>). For <jats:styled-content style=\"fixed-case\">PHN<\/jats:styled-content> of the first division of the fifth cranial nerve (ophthalmic division of the trigeminal ganglion), there is evidence of inflammatory change in the ganglion and adjacent ocular neural structures. First division trigeminal nerve <jats:styled-content style=\"fixed-case\">PHN<\/jats:styled-content> can prove to be difficult and sometimes even impossible to manage despite the use of a wide range of conservative measures, including anticonvulsant and antidepressant medication. Steroids have been shown to play an important role by suppressing neural inflammatory processes. We therefore chose the trigeminal ganglion as an interventional target for an 88\u2010year\u2010old woman with severe ophthalmic division <jats:styled-content style=\"fixed-case\">PHN<\/jats:styled-content> after she failed to respond to conservative treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Under fluoroscopic guidance, a trigeminal ganglion nerve block was performed with lidocaine combined with dexamethasone. A retrobulbar block with lidocaine and triamcinolone settled residual oculodynia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 1\u2010year follow\u2010up, the patient remained pain free and did not require analgesic medication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>To our knowledge, this is the first reported case of ophthalmic division <jats:styled-content style=\"fixed-case\">PHN<\/jats:styled-content> successfully treated with a combination of trigeminal ganglion and retrobulbar nerve block using a local anesthetic agent and steroid for central and peripheral neural inflammatory processes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/papr.12547","type":"journal-article","created":{"date-parts":[[2016,12,20]],"date-time":"2016-12-20T13:12:41Z","timestamp":1482239561000},"page":"961-967","source":"Crossref","is-referenced-by-count":9,"title":["Gasserian Ganglion and Retrobulbar Nerve Block in the Treatment of Ophthalmic 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