{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T22:11:11Z","timestamp":1785190271311,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,3,17]],"date-time":"2017-03-17T00:00:00Z","timestamp":1489708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Previous pilot studies suggest the presence of heterogeneous sensitivity to pressure in primary headaches without considering the frequency of headache episodes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the differences in topographical pressure pain sensitivity maps in the temporalis muscle between individuals with frequent episodic (<jats:styled-content style=\"fixed-case\">FETTH<\/jats:styled-content>) and chronic (<jats:styled-content style=\"fixed-case\">CTTH<\/jats:styled-content>) tension\u2010type headache by controlling the presence of anxiety and depression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>oPressure pain thresholds (<jats:styled-content style=\"fixed-case\">PPT<\/jats:styled-content>s) were assessed bilaterally from 9 points distributed over the temporalis muscle (3 points in the anterior portion, 3 in the middle portion, and the remaining 3 in the posterior portion of the muscle belly) in 113 patients with <jats:styled-content style=\"fixed-case\">FETTH<\/jats:styled-content> and 91 with <jats:styled-content style=\"fixed-case\">CTTH<\/jats:styled-content> in a blinded design. Topographical pressure pain sensitivity maps based on interpolation of the <jats:styled-content style=\"fixed-case\">PPT<\/jats:styled-content>s were constructed. Clinical features of headache were collected in a 4\u2010week headache diary. Anxiety and depression (Hospital Anxiety and Depression Scale) were also assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The multilevel analysis of covariance found significant difference in <jats:styled-content style=\"fixed-case\">PPT<\/jats:styled-content> levels between points (<jats:italic>F<\/jats:italic> = 47.649; <jats:italic>P<\/jats:italic> &lt; 0.001), but not between groups (<jats:italic>F<\/jats:italic> = 0.801; <jats:italic>P<\/jats:italic> = 0.602) or sides (<jats:italic>F<\/jats:italic> = 0.331; <jats:italic>P<\/jats:italic> = 0.565). No significant effect of gender (<jats:italic>F<\/jats:italic> = 0.785; <jats:italic>P<\/jats:italic> = 0.667), depression (<jats:italic>F<\/jats:italic> = 0.515; <jats:italic>P<\/jats:italic> = 0.846), or anxiety (<jats:italic>F<\/jats:italic> = 0.639; <jats:italic>P<\/jats:italic> = 0.745) was observed. Post hoc comparisons revealed: (1) no differences between <jats:styled-content style=\"fixed-case\">FETTH<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CTTH<\/jats:styled-content>; (2) no side\u2010to\u2010side differences; and (3) anterior\u2010to\u2010posterior gradient with the most sensitive points located in the anterior column, followed by those located in the central column and the posterior column of the muscle (all, <jats:italic>P<\/jats:italic> &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study confirmed an anterior\u2010to\u2010posterior gradient of sensitivity to pressure in both groups, with the highest sensitivity at the anterior part of the muscle. Further, we found similar pressure pain sensitivity in the trigeminal area in people with <jats:styled-content style=\"fixed-case\">FETTH<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">CTTH<\/jats:styled-content> with no association with depressive or anxiety levels.<\/jats:p><\/jats:sec>","DOI":"10.1111\/papr.12565","type":"journal-article","created":{"date-parts":[[2017,2,22]],"date-time":"2017-02-22T22:26:38Z","timestamp":1487802398000},"page":"1050-1057","source":"Crossref","is-referenced-by-count":6,"title":["Topographical Pressure Pain Sensitivity Maps of the Temporalis Muscle in People with Frequent Episodic and Chronic Tension\u2010Type Headache"],"prefix":"10.1111","volume":"17","author":[{"given":"Mar\u00eda","family":"Palacios Ce\u00f1a","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation Universidad Rey Juan Carlos Alcorc\u00f3n Spain"},{"name":"Sensory and Motor Interaction (SMI) Center Department of Health Science and Technology Faculty of Medicine Aalborg University Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Castaldo","sequence":"additional","affiliation":[{"name":"Sensory and Motor Interaction (SMI) Center Department of Health Science and Technology Faculty of Medicine Aalborg University Aalborg Denmark"},{"name":"Department of Physical Therapy University of Siena Siena Italy"},{"name":"Poliambulatorio Fisiocenter Collecchio Parma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelun","family":"Wang","sequence":"additional","affiliation":[{"name":"Sensory and Motor Interaction (SMI) Center Department of Health Science and Technology Faculty of Medicine Aalborg University Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Madeleine","sequence":"additional","affiliation":[{"name":"Physical Activity and Human Performance Group Sensory and Motor Interaction (SMI) Center Department of Health Science and Technology Aalborg University Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1ngel L.","family":"Guerrero","sequence":"additional","affiliation":[{"name":"Headache Unit Hospital Cl\u00ednico Universitario de Valladolid Valladolid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Arendt\u2010Nielsen","sequence":"additional","affiliation":[{"name":"Sensory and Motor Interaction (SMI) Center Department of Health Science and Technology Faculty of Medicine Aalborg University Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9sar","family":"Fern\u00e1ndez\u2010de\u2010las\u2010Pe\u00f1as","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation Universidad Rey Juan Carlos Alcorc\u00f3n Spain"},{"name":"Sensory and Motor Interaction (SMI) Center Department of Health Science and Technology Faculty of Medicine Aalborg University Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12650"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-14-40"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-013-1370-4"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ane.12339"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60692-4"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-014-0469-5"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573397112666151231113625"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413492913"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000219"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2009.11.001"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.math.2015.07.002"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2011.04.001"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20189"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-11-234"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2007.01005.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2009.01901.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413485658"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01239.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(99)00101-3"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2005.01.352"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2011.3666"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e318154b6ae"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1145\/800186.810616"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(01)00296-3"},{"key":"e_1_2_7_27_1","first-page":"749","article-title":"Use of the Hospital Anxiety and Depression Scale as a screening tool for patients with headache","volume":"62","author":"Juang KD","year":"1999","journal-title":"Zhonghua Yi Xue Za Zhi (Taipei)."},{"key":"e_1_2_7_28_1","first-page":"1","article-title":"Pressure pain threshold mapping: a new imaging modality of muscle sensitivity to pain","volume":"2","author":"Binderup A","year":"2008","journal-title":"IEEE Xplore."},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2008.01831.x"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(98)01302-2"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2006.09.037"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.2003.00570.x"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2006.01.040"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.10.023"}],"container-title":["Pain Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpapr.12565","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/papr.12565","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T10:47:55Z","timestamp":1695552475000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/papr.12565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,17]]},"references-count":33,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/papr.12565"],"URL":"https:\/\/doi.org\/10.1111\/papr.12565","archive":["Portico"],"relation":{},"ISSN":["1530-7085","1533-2500"],"issn-type":[{"value":"1530-7085","type":"print"},{"value":"1533-2500","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,17]]}}}