{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:13:46Z","timestamp":1788542026852,"version":"build-2803163510"},"reference-count":10,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T00:00:00Z","timestamp":1523923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai","doi-asserted-by":"publisher","award":["15ZR1407200"],"award-info":[{"award-number":["15ZR1407200"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81372101"],"award-info":[{"award-number":["81372101"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To explore the feasibility, effectiveness, and safety of ultrasound\u2010guided intercostal nerve block (<jats:styled-content style=\"fixed-case\">ICNB<\/jats:styled-content>) for immediate relief of moderate and severe pain following esophagectomy in a postanesthesia care unit (<jats:styled-content style=\"fixed-case\">PACU<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty\u2010one patients who complained of moderate to severe pain on arrival to the <jats:styled-content style=\"fixed-case\">PACU<\/jats:styled-content> after an Ivor Lewis esophagectomy were randomly assigned to 2 groups: a sufentanil treatment group (Group A, <jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>41) and an intercostal nerve block treatment group (Group B, <jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>40). The visual analog scale (<jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content>) pain scores at rest and on cough at 1, 2, 4, 12, 24, and 48\u00a0hours after treatment were monitored. The heart rate, blood pressure, and pulse oxygen saturation (SpO<jats:sub>2<\/jats:sub>) 2\u00a0hours after treatment and the patients\u2019 length of stay in the <jats:styled-content style=\"fixed-case\">PACU<\/jats:styled-content> after treatment were recorded. Patient\u2010controlled intravenous analgesia consumption and the incidence of nausea, vomiting, and other adverse reactions were also recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ultrasound\u2010guided <jats:styled-content style=\"fixed-case\">ICNB<\/jats:styled-content> was performed successfully in all patients in Group B without puncture\u2010related complications. The <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content> pain scores at rest and on cough at 1, 2, and 4\u00a0hours after treatment in Group B were significantly lower than those in Group A (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.05). The consumption of sufentanil and the incidence of nausea and vomiting were significantly decreased in Group B compared with those in Group A.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Ultrasound\u2010guided <jats:styled-content style=\"fixed-case\">ICNB<\/jats:styled-content> could provide effective and safe pain relief for patients who suffer from moderate to severe pain (<jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content> score\u00a0\u2265\u00a05) after esophagectomy in the <jats:styled-content style=\"fixed-case\">PACU<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/papr.12689","type":"journal-article","created":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T16:03:50Z","timestamp":1519661030000},"page":"879-883","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Ultrasound\u2010Guided Intercostal Nerve Block Following Esophagectomy for Acute Postoperative Pain Relief in the Postanesthesia Care Unit"],"prefix":"10.1111","volume":"18","author":[{"given":"Mengqi","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Shanghai Cancer Center Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuechao","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Shanghai Cancer Center Fudan University Shanghai China"},{"name":"Department of Oncology Shanghai Medical College Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Shanghai Cancer Center Fudan University Shanghai China"},{"name":"Department of Oncology Shanghai Medical College Fudan University Shanghai 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University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,4,17]]},"reference":[{"issue":"1","key":"e_1_2_9_2_1","first-page":"S62","article-title":"Postoperative pain management","volume":"7","author":"Kolettas A","year":"2015","journal-title":"J Thorac Dis"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60245-6"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.13358"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00101-013-2253-z"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jopan.2004.03.008"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jopan.2010.07.007"},{"key":"e_1_2_9_8_1","article-title":"Opioids and the immune system\u2014friend or foe","author":"Plein LM","year":"2017","journal-title":"Br J 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