{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T21:31:47Z","timestamp":1785879107597,"version":"3.56.0"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Trigeminal neuralgia (TN) is the most common cause of facial pain, leading to significant disability and impacting a patient's quality of life. Percutaneous procedures like continuous radiofrequency, pulsed radiofrequency (PRF), and combined continuous and pulsed radiofrequency have been studied in past years comparing different voltages in order to find more effective therapies with fewer complications (eg, numbness and masseter muscle weakness). With regard to young patients, there is still insufficient evidence on the most appropriate procedure in this patient population. PRF does not cause thermal damage. The mechanism of action involves delivering an electrical field to targeted nerves or tissues, modulating pain. We propose that bipolar pulsed radiofrequency (2 parallel cannulas) in the trigeminal ganglion produce a denser and larger field resulting in more effective controlled pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>We present 2 cases of 40\u2010 and 48\u2010year\u2010old men with severe V2 to V3 TN who underwent bipolar PRF. We performed bipolar PRF on the trigeminal ganglion through the foramen ovale using two 22\u2010gauge 100\u2010mm cannulas with 10\u2010mm active tips. Parameters used were voltage of 85\u00a0V, pulse width of 20\u00a0milliseconds, and total duration time of 6\u00a0minutes. Both patients reported complete relief of pain after the procedure, and at 2\u2010year follow\u2010up they were pain free and experienced a better quality of life. No complications were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Bipolar PRF could be a non\u2010neurodestructive option for young people with TN and deserves further investigation as a treatment option.<\/jats:p><\/jats:sec>","DOI":"10.1111\/papr.12944","type":"journal-article","created":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T21:51:29Z","timestamp":1597355489000},"page":"343-347","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Bipolar Pulsed Radiofrequency for Trigeminal Neuralgia: A Report of Two Cases"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3275-5881","authenticated-orcid":false,"given":"Victor","family":"Silva","sequence":"first","affiliation":[{"name":"Pain Management Center Centro Medico Zambrano Hellion  San Pedro Garza Garc\u00eda Nuevo Leon Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miles","family":"Day","sequence":"additional","affiliation":[{"name":"Pain Research The Pain Center at Grace Clinic Texas Tech University HSC Lubbock Texas U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarita","family":"Santiago","sequence":"additional","affiliation":[{"name":"Pain Management Center Centro Medico Zambrano Hellion  San Pedro Garza Garc\u00eda Nuevo Leon Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-018-0964-9"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000005247"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000004940"},{"key":"e_1_2_7_6_1","first-page":"E873","article-title":"Effects of pulsed versus conventional versus combined radiofrequency for the treatment of trigeminal neuralgia: a prospective study","volume":"20","author":"Elawamy A","year":"2017","journal-title":"Pain Physician"},{"key":"e_1_2_7_7_1","first-page":"595","article-title":"Comparison of high voltage with standard\u2010voltage pulsed radiofrequency of Gasserian ganglion in the treatment of idiopathic trigeminal neuralgia","volume":"15","author":"Luo 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