{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T07:54:09Z","timestamp":1771919649045,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T00:00:00Z","timestamp":1612828800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Transforaminal epidural steroid injection (TFESI) is widely practiced for the treatment of radicular pain. As its effectiveness is still subject to debate, a better patient selection for TFESI is necessary. We aimed to evaluate the potential of bedside\u2010suitable qualitative sensory testing (QualST) to determine the early effectiveness of TFESI for the treatment of chronic lumbosacral radiculopathy (LSR)\u2010related pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010six patients with chronic painful unilateral LSR were evaluated in a prospective observational study using five standardized sensory tests (10\u00a0g monofilament, 200 to 400\u00a0mN brush, Lindblom rollers with controlled 25 and 40\u00b0C temperature, and 40\u00a0g neurological pin). Quality of sensory perceptions on the painful leg was compared to the non\u2010painful leg and rated as normal sensitivity, hyposensitivity, or hypersensitivity. Pain and related characteristics were evaluated before TFESI, 1\u00a0week after and 4\u00a0weeks after intervention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven sensory phenotypes were distinguished according to individual sets of sensory disturbances acquired with five sensory tests. Patients were grouped into four groups of allied phenotypes (normal sensitivity, hyposensitivity to 1 to 3 modalities, hyposensitivity to 4 to 5 modalities, and hypersensitivity). The whole study group showed significant improvement in most parameters of outcome measurements. Statistical analysis revealed some significant differences between sensory groups in patient\u2010reported treatment effect scales after 4\u00a0weeks. We also detected significant differences between sensory groups in repeated measures after 1 and 4\u00a0weeks in some pain intensity characteristics and patient\u2010reported treatment effect scales.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>QualST might be clinically applicable for detecting patient subgroups that could differ in the early treatment results of radicular pain by TFESI.<\/jats:p><\/jats:sec>","DOI":"10.1111\/papr.12997","type":"journal-article","created":{"date-parts":[[2021,1,27]],"date-time":"2021-01-27T13:33:24Z","timestamp":1611754404000},"page":"618-629","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Qualitative Sensory Testing in Outcome Prediction of Transforaminal Epidural Steroid Injection for Chronic Painful Unilateral Lumbosacral Radiculopathy: Prospective Observational Study"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5869-7726","authenticated-orcid":false,"given":"Alfredas","family":"Vaitkus","sequence":"first","affiliation":[{"name":"Clinic of Anaesthesiology and Intensive Care Institute of Clinical Medicine Faculty of Medicine Vilnius University Vilnius Lithuania"},{"name":"Centre of Anaesthesiology, Intensive Therapy and Pain Management Vilnius University Hospital Santaros Klinikos Vilnius Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7099-1741","authenticated-orcid":false,"given":"J\u016brat\u0117","family":"\u0160ipylait\u0117","sequence":"additional","affiliation":[{"name":"Clinic of Anaesthesiology and Intensive Care Institute of Clinical Medicine Faculty of Medicine Vilnius University Vilnius Lithuania"},{"name":"Centre of Anaesthesiology, Intensive Therapy and Pain Management Vilnius University Hospital Santaros Klinikos Vilnius 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