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The objectives of this study were to identify biopsychosocial factors associated with acute postsurgical pain trajectories and with pain intensity and interference after 1, 3, and 12 months. Two hundred ten patients listed for joint arthroplasty filled a presurgical battery of questionnaires assessing presurgical pain intensity, catastrophizing, emotional distress, state anxiety and depression, self\u2010efficacy, central sensitization, and executive functions. From the day after surgery, they were asked to fill a 7\u2010day diary, including questions about postsurgical pain and postsurgical state catastrophizing. Finally, they provided data about pain intensity and interference after 1, 3, and 12 months. Predictors of acute pain trajectories were investigated using multilevel growth curve analysis. Results showed that central sensitization was a predictor of the intercept of pain trajectories and daily postsurgical catastrophizing was a significant covariate of pain intensity in the acute phase. Analyses of follow\u2010up data showed that central sensitization was a predictor of pain intensity and pain interference at 3 and 12 months, that emotional distress was related with pain intensity and interference at 1 month, and with pain interference at 3 months, and that cognitive flexibility was associated with pain interference at 1 month. Assessment of these factors could enable to identify patients at risk for worse outcomes and to plan targeted treatments to be implemented during the patient\u2019s inward stay.<\/jats:p>","DOI":"10.1111\/papr.13074","type":"journal-article","created":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T07:18:40Z","timestamp":1631171920000},"page":"159-170","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Psychological factors and trajectories of post\u2010surgical pain: A longitudinal prospective study"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5767-8785","authenticated-orcid":false,"given":"Emanuele M.","family":"Giusti","sequence":"first","affiliation":[{"name":"Department of Psychology Catholic University of Milan  Milan Italy"},{"name":"Psychology Research Laboratory Istituto Auxologico Italiano IRCCS  Milan 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