{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:58:51Z","timestamp":1791907131747,"version":"4.3.4"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T00:00:00Z","timestamp":1657411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Ultrasound\u2010guided quadratus lumborum block (QLB) is considered a novel nerve block for postoperative pain control. However, its efficacy after urological surgery remains unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The purpose of the current meta\u2010analysis was to evaluate the effects of the QLB block versus control (placebo or no injection) on postoperative pain and other adverse outcomes after urological surgery, providing extensive evidence of whether quadratus lumborum block is suitable for pain management after urological surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Systematic review with meta\u2010analysis of randomized clinical trials.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We searched PubMed, Cochrane Library, Embase, Web of Science, and <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link> to collect studies investigating the effects of QLB on analgesia after urological surgery. The primary outcomes included visual analog scale (VAS) at rest and during movement, 24\u2010h postoperative morphine consumption, and the incidence of postoperative nausea and vomiting (PONV).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 13 randomized controlled trials (RCTs) were reviewed, including 751 patients who underwent urological surgery. The QLB group exhibited a lower VAS score postoperatively at rest or on movement at 0, 6, 12, and 24\u2009h, with less 24\u2010h postoperative morphine consumption and lower incidence of PONV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Limitations<\/jats:title><jats:p>Although the result is stable, heterogeneity exists in the current research.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>QLB exhibited a favorable effect of postoperative analgesia with reduced postoperative complications at rest or during movement after urological surgery. However, it is still a novel technology at a primary stage, which needs further research to develop.<\/jats:p><\/jats:sec>","DOI":"10.1111\/papr.13140","type":"journal-article","created":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T06:29:47Z","timestamp":1655792987000},"page":"70-82","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Efficacy of quadratus lumborum block on postoperative pain and side effects in patients who underwent urological surgery: A\u00a0meta\u2010analysis"],"prefix":"10.1111","volume":"23","author":[{"given":"Qiang","family":"Cai","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and Science  Xiangyang China"},{"name":"Department of Anesthesiology, Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and Science  Xiangyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqing","family":"Liu","sequence":"additional","affiliation":[{"name":"Guangxi Medical University  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zengchen","family":"Liu","sequence":"additional","affiliation":[{"name":"Guangxi Medical University  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiling","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linsheng","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuhai","family":"He","sequence":"additional","affiliation":[{"name":"Guangxi Medical University  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shangyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Guangxi Medical University  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunhua","family":"Lin","sequence":"additional","affiliation":[{"name":"Guangxi Medical University  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huixia","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiqian","family":"Dou","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dexi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and Science  Xiangyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6866-6253","authenticated-orcid":false,"given":"Xingrui","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and Science  Xiangyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-020-00967-2"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000268392.05157.a8"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000003611"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rapm.2007.06.268"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000002524"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0000000000000299"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-019-3359-7"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g7647"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(95)00134-4"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2019.07.027"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-5-13"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-198836030-00003"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.13179"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"e_1_2_11_16_1","first-page":"1135","article-title":"The introduction of using new version of guideline development tool (GRADE pro GDT) in the systematic reviews of the intervention studies","volume":"18","author":"Chen H","year":"2018","journal-title":"Chinese J Evid Based Med"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.24920\/003759"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2020-101745"},{"key":"e_1_2_11_19_1","first-page":"1647","article-title":"Analgesic effect of ultrasound\u2010guided preoperative unilateral lateral quadratus lumborum block for laparoscopic nephrectomy: a randomized, double\u2010blinded","volume":"13","author":"Kwak KH","year":"2020","journal-title":"Controlled Trial J Pain Res"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0000000000001433"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.4103\/ija.IJA_335_20"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-019-0825-4"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/11101849.2021.1894661"},{"key":"e_1_2_11_24_1","first-page":"367","article-title":"Quadratus lumborum block (transmuscular approach) versus transversus abdominis plane block (unilateral subcostal approach) for perioperative analgesia in patients undergoing open nephrectomy: a randomized, double\u2010blinded, controlled trial","volume":"71","author":"Saleh AH","year":"2021","journal-title":"Brazil J Anesthesiol"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2019.04.054"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.5152\/TJAR.2018.92331"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.4097\/kja.19175"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.4103\/ija.IJA_21_20"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/21681805.2019.1658636"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0000000000000366"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2016.12.013"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e318230f6c1"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.23736\/S0375-9393.20.13975-0"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1159\/000052351"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-019-07013-4"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2017.05.035"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200059020-00005"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.1999.00998.x"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002888"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2017.11.020"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2020.109715"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2020.110003"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2017.11.084"}],"container-title":["Pain Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/papr.13140","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/papr.13140","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/papr.13140","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T09:45:08Z","timestamp":1692438308000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/papr.13140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,10]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1111\/papr.13140"],"URL":"https:\/\/doi.org\/10.1111\/papr.13140","archive":["Portico"],"relation":{},"ISSN":["1530-7085","1533-2500"],"issn-type":[{"value":"1530-7085","type":"print"},{"value":"1533-2500","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,10]]},"assertion":[{"value":"2021-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}