{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:23:49Z","timestamp":1787505829007,"version":"build-2736575974"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,2,5]],"date-time":"2023-02-05T00:00:00Z","timestamp":1675555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Our meta\u2010analysis aimed to compare the analgesic effectiveness of ultrasound\u2010guided preoperative erector spinae plane block (ESPB) versus paravertebral nerve block (PVB) in breast surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed, EMBASE, and the Cochrane Library were searched for randomized controlled trials (RCTs) between January 1, 1980 and April 31, 2021. The primary endpoints were perioperative pain score, analgesic consumption, and assessment of the block procedure. The secondary endpoints were intraoperative hemodynamic response, duration of surgery, postoperative antiemetic consumption, and adverse effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Four RCTs comprised a total of 310 patients were included in our meta\u2010analysis. No significant differences in the perioperative pain score and analgesic consumption were observed between ESPB and PVB in the operating room, post\u2010anesthesia care unit (PACU), and ward (at 1, 16, 12, and 24\u2009h), and the morning of postoperative day 1 (POD1) (all\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&gt;\u20090.05). Similarly, no significant differences in the duration of block, time to first analgesic, hemodynamic response, duration of surgery, postoperative antiemetic consumption, and adverse effects were observed (all\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&gt;\u20090.05). However, our meta\u2010analysis revealed that ultrasound\u2010guided preoperative ESPB significantly reduced the duration of procedure time and frequency of guidance interventions, as well as increased the block success rate among residents (all\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Both ultrasound\u2010guided preoperative ESPB and PVB showed comparable analgesic effects in patients undergoing breast surgery. However, with a significantly shorter procedure time and higher block success rate, our findings suggest that ESPB may be a simple alternative to PVB in breast surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/papr.13208","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T07:54:36Z","timestamp":1674633276000},"page":"511-522","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Analgesic effectiveness of preoperative ultrasound\u2010guided erector spinae plane block versus paravertebral nerve block for breast surgery: A systematic review and meta\u2010analysis of four randomized controlled trials"],"prefix":"10.1111","volume":"23","author":[{"given":"Wei","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofeng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Pain, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Ankang Central Hospital Hubei University of Medicine  Ankang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, People's Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Neuro\u2010Critical Care Medicine, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juying","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neuro\u2010Critical Care Medicine, Taihe Hospital Hubei University of Medicine  Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1010661530585"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2006.02.007"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f1865"},{"issue":"12","key":"e_1_2_11_5_1","first-page":"65","article-title":"An evidence\u2010based review of the efficacy of perioperative analgesic techniques for breast cancer\u2010related surgery","volume":"46","author":"Cheng GS","year":"2016","journal-title":"Pain Med"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3344\/kjp.2019.32.3.206"},{"issue":"14","key":"e_1_2_11_7_1","first-page":"11","article-title":"Breast surgery using thoracic paravertebral blockade and sedation alone","volume":"20","author":"Simpson J","year":"2014","journal-title":"Anesthesiol Res Pract"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000136775.15566.87"},{"issue":"12","key":"e_1_2_11_9_1","first-page":"215","article-title":"Breast surgery using thoracic paravertebral blockade and sedation alone","volume":"18","author":"Simpson J","year":"2014","journal-title":"Anesthesiol Res Pract"},{"issue":"24","key":"e_1_2_11_10_1","first-page":"1214","article-title":"Effects of ultrasound\u2010guided thoracic paravertebral block combined with general anesthesia on the secretion of pain\u2010related mediators after modified radical mastectomy","volume":"9","author":"Cheng L","year":"2018","journal-title":"J Hainan Med Univ"},{"issue":"16","key":"e_1_2_11_11_1","first-page":"324","article-title":"Efficacy and safety of paravertebral blocks in breast surgery: a meta\u2010analysis of randomized controlled trials","volume":"26","author":"Schnabel A","year":"2010","journal-title":"Br J Anaesth"},{"issue":"8","key":"e_1_2_11_12_1","first-page":"124","article-title":"Thoracic paravertebral blockade in breast surgery: is pneumothorax an appreciable concern? 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