{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:04:43Z","timestamp":1790391883630,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T00:00:00Z","timestamp":1693699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pain Practice"],"published-print":{"date-parts":[[2024,1]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n \n The MOTION study is designed to measure the impact of percutaneous image\u2010guided lumbar decompression as a first\u2010line therapy on patients otherwise receiving real\u2010world conventional medical management for lumbar spinal stenosis with neurogenic claudication secondary to hypertrophic ligamentum flavum. This prospective, multicenter randomized controlled trial uses objective and patient\u2010reported outcome measures to compare the combination of the\n mild<\/jats:italic>\n \u00ae percutaneous treatment and nonsurgical conventional medical management (CMM) to CMM\u2010Alone.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Test group patients received the\n mild<\/jats:italic>\n procedure after study enrollment. Test and control groups were allowed conventional conservative therapies and low\u2010risk interventional therapies as recommended by their physicians. Subjective outcomes included the Oswestry Disability Index, Numeric Pain Rating Scale, and Zurich Claudication Questionnaire. Objective outcomes included a validated Walking Tolerance Test, the rate of subsequent lumbar spine interventions, and safety data.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Two\u2010year follow\u2010up included 64\n mild<\/jats:italic>\n \u2009+\u2009CMM and 67 CMM\u2010Alone patients. All outcome measures showed significant improvement from baseline for\n mild<\/jats:italic>\n \u2009+\u2009CMM, whereas the majority of CMM\u2010Alone patients had elected to receive\n mild<\/jats:italic>\n treatment or other lumbar spine interventions by 2\u2009years, precluding valid 2\u2010year between\u2010group comparisons. Neither group reported any device\u2010 or procedure\u2010related adverse events.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n The durability of\n mild<\/jats:italic>\n \u2009+\u2009CMM for this patient population was demonstrated for all efficacy outcomes through 2\u2009years. Improvements in walking time from baseline to 2\u2009years for patients treated with\n mild<\/jats:italic>\n \u2009+\u2009CMM were significant and substantial. The lack of reported device or procedure\u2010related adverse events reinforces the strong safety profile of the\n mild<\/jats:italic>\n procedure. These results provide support for early interventional treatment of symptomatic LSS with the\n mild<\/jats:italic>\n procedure.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/papr.13293","type":"journal-article","created":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T00:36:07Z","timestamp":1693787767000},"page":"109-119","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The MOTION study: Two\u2010year results of a real\u2010world randomized controlled trial of the\n mild<\/i>\n \u00ae procedure for treatment of lumbar spinal stenosis"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8907-7730","authenticated-orcid":false,"given":"Timothy R.","family":"Deer","sequence":"first","affiliation":[{"name":"The Spine & Nerve Centers of the Virginias Charleston West Virginia 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-009-0919-7"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200103000-00016"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3233\/THC-161139"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS-20-08-527"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.2217\/pmt-2020-0037"},{"issue":"7","key":"e_1_2_8_7_1","first-page":"789","article-title":"Long\u2010term safety and efficacy of minimally invasive lumbar decompression procedure for the treatment of lumbar spinal stenosis with neurogenic claudication: 2\u2010year results of MiDAS ENCORE","volume":"43","author":"Staats PS","year":"2018","journal-title":"Reg Anesth Pain 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