{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:13:06Z","timestamp":1790748786034,"version":"4.1.0"},"reference-count":61,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,10,3]],"date-time":"2017-10-03T00:00:00Z","timestamp":1506988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychol Psychother"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      This study sought to investigate how people who had tested positive for the Huntington's disease (\n                      <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>\n                      ) gene mutation understood and experienced psychological distress and their expectations of psychological therapy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>\n                      A qualitative methodology was adopted involving semi\u2010structured interviews and interpretative phenomenological analysis (\n                      <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      A total of nine participants (five women and four men) who had opted to engage in psychological therapy were recruited and interviewed prior to the start of this particular psychological therapeutic intervention. Interviews were transcribed verbatim and analysed using\n                      <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content>\n                      whereby themes were analysed within and across transcripts and classified into superordinate themes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Three superordinate themes were developed: Attributing psychological distress to\n                      <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>\n                      : \u2018you're blaming everything on that now\u2019; Changes in attributions of distress over time: \u2018in the past you'd just get on with it\u2019; and Approaching therapy with an open mind, commitment, and hope: \u2018a light at the end of the tunnel\u2019.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Understandings of psychological distress in\n                      <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>\n                      included biological and psychological explanations, with both often being accepted simultaneously by the same individual but with biomedical accounts generally dominating. Individual experience seemed to reflect a dynamic process whereby people's understanding and experience of their distress changed over time. Psychological therapy was accepted as a positive alternative to medication, providing people with\n                      <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>\n                      with hope that their psychological well\u2010being could be enhanced.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Practitioner points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>People with the Huntington's disease gene mutation have largely biomedical understandings of their psychological distress.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>This largely biomedical understanding does not, however, preclude them for being interested in the potential gains resulting from psychological therapy.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>The mechanisms of psychological therapy should be explained in detail before therapy and explored along with current attributions of distress.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/papt.12157","type":"journal-article","created":{"date-parts":[[2017,10,3]],"date-time":"2017-10-03T09:16:40Z","timestamp":1507022200000},"page":"216-231","source":"Crossref","is-referenced-by-count":20,"title":["Understandings of psychological difficulties in people with the Huntington's disease gene and their expectations of psychological therapy"],"prefix":"10.1111","volume":"91","author":[{"given":"Rachael","family":"Theed","sequence":"first","affiliation":[{"name":"Division of Health Research Lancaster University UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1484-2703","authenticated-orcid":false,"given":"Fiona J. 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