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While common in clinical trials, participant experiences of cotherapy remain underexplored. This study explored cotherapy experiences in\n                      <jats:styled-content style=\"fixed-case\">PAT<\/jats:styled-content>\n                      with psilocybin for Generalised Anxiety Disorder (\n                      <jats:styled-content style=\"fixed-case\">GAD<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>\n                      Longitudinal qualitative analysis of participants sampled from a large randomised, open\u2010label, phase 2 clinical trial of psilocybin\u2010assisted therapy for\n                      <jats:styled-content style=\"fixed-case\">GAD<\/jats:styled-content>\n                      , delivered by clinicians with high levels of qualification, training and supervision.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Qualitative data were collected from\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200918 participants via 29 semi\u2010structured interviews, conducted before and after dosing sessions. Interviews examined experiences of\n                      <jats:styled-content style=\"fixed-case\">PAT<\/jats:styled-content>\n                      with a cotherapy dyad. Data were analysed thematically, guided by Affordance Theory to consider how cotherapy dynamics shaped therapeutic possibilities.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Three major themes were developed: (1) dose day cotherapy: safety, trust and the realities of access; (2) cotherapy influences therapeutic processes; and (3) cotherapy shapes the impact and credibility of therapeutic insights.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Cotherapy in\n                      <jats:styled-content style=\"fixed-case\">PAT<\/jats:styled-content>\n                      can be both a safety and supportive measure, and a potentiator of therapeutic processes. Insights from this study can guide clinical practice and future research to harness the potential safety and therapeutic benefits afforded by cotherapy while considering feasibility and accessibility.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/papt.70098","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T07:51:47Z","timestamp":1786348307000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["\u2018So many relationships in the room\u2019: Participant perspectives on the affordances and challenges of co\u2010therapy in psychedelic assisted therapy"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0744-6924","authenticated-orcid":false,"given":"Rachel","family":"Ham","sequence":"first","affiliation":[{"name":"Department of Psychiatry, School of Clinical Sciences Monash University  Clayton Victoria Australia"},{"name":"School 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