{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T21:53:40Z","timestamp":1789422820690,"version":"build-2803163510"},"reference-count":76,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T00:00:00Z","timestamp":1737331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Plant Cell &amp; Environment"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Flower color is a crucial trait that attracts pollinators and determines the ornamental value of floral crops.\n                    <jats:italic>Cymbidium lowianum<\/jats:italic>\n                    , one of the most important breeding parent of\n                    <jats:italic>Cymbidium<\/jats:italic>\n                    hybrids, has two flower morphs (normal and albino) that differ in flower lip color. However, the molecular mechanisms underlying flower color formation in\n                    <jats:italic>C. lowianum<\/jats:italic>\n                    are not well understood. In this study, comparative metabolomic analysis between normal and albino flower lip tissues indicated that cyanidin\u20103\u2010\n                    <jats:italic>O<\/jats:italic>\n                    \u2010glucoside content was significantly higher in red epichiles than in other lip tissues. This finding suggests that cyanidin\u20103\u2010\n                    <jats:italic>O<\/jats:italic>\n                    \u2010glucoside is responsible for color variation and differentiation in the lip in\n                    <jats:italic>C. lowianum<\/jats:italic>\n                    . We also found that red coloration in\n                    <jats:italic>C. lowianum<\/jats:italic>\n                    flower is correlated with high levels of\n                    <jats:italic>F3'H<\/jats:italic>\n                    expression; further, anthocyanins, carotenoids and chlorophyll coordinate to influence sepal and petal coloration during flower development. In transgenic Arabidopsis lines, overexpression of\n                    <jats:italic>F3'H<\/jats:italic>\n                    increased anthocyanin concentration, overexpression of\n                    <jats:italic>BCH<\/jats:italic>\n                    increased carotenoid concentration, whereas overexpression of\n                    <jats:italic>HEMG<\/jats:italic>\n                    and\n                    <jats:italic>CHLI<\/jats:italic>\n                    both increased chlorophyll concentration. Identification and assessment of several transcription factors revealed that MYB308\u20101 activates\n                    <jats:italic>BCH<\/jats:italic>\n                    , MYB111 and PIF4\u20102 activate\n                    <jats:italic>HEMG<\/jats:italic>\n                    and\n                    <jats:italic>CHLI<\/jats:italic>\n                    expression during flower development. Importantly, MYB14\u20101 shows interaction with PIF4\u20102, and appears to act as a connector between anthocyanin and chlorophyll biosynthesis by either activating\n                    <jats:italic>F3'H<\/jats:italic>\n                    expression or inhibiting\n                    <jats:italic>CHLI<\/jats:italic>\n                    expression. These results indicate that, in\n                    <jats:italic>C. lowianum<\/jats:italic>\n                    , variation in flower color and differentiation of lip color patterns are primarily regulated by the types and concentrations of flavonoids; further, carotenoids and chlorophyll also influence flower coloration during development.\n                  <\/jats:p>","DOI":"10.1111\/pce.15398","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T00:42:01Z","timestamp":1737420121000},"page":"3844-3860","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Spatial and Temporal Regulation of Flower Coloration in\n                    <i>Cymbidium lowianum<\/i>"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4865-8771","authenticated-orcid":false,"given":"Xiu\u2010Mei","family":"Dong","sequence":"first","affiliation":[{"name":"Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany Chinese Academy of Sciences Kunming Yunnan China"},{"name":"Yunnan Key Laboratory for Wild Plant Resources Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany Chinese Academy of Sciences Kunming Yunnan China"},{"name":"Yunnan Key Laboratory for Wild Plant Resources Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengling","family":"Tu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany Chinese Academy of Sciences Kunming Yunnan China"},{"name":"Yunnan Key Laboratory for Wild Plant Resources Kunming Yunnan China"},{"name":"University of Chinese Academy of Sciences Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi\u2010Bao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany Chinese Academy of Sciences Kunming Yunnan China"},{"name":"Yunnan Key Laboratory for Wild Plant Resources Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/138920211796429754"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/pbi.13114"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13007-024-01197-0"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2015.05.007"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23020738"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envexpbot.2023.105618"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/pce.14684"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/plb.13680"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2021.685136"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiotec.2004.02.019"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2016.06.006"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpj.2020.10.002"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.7.7.1071"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.114.254599"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.19.00205"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099728"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2013.06.003"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.110.158279"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-020-02553-7"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-020-07028-5"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods10030527"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2017.00341"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-020-0821-8"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2017.01.019"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/pbi.14193"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00425-022-03840-3"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-021-03256-3"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/eraa327"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2024.1396875"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2023.107835"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222312824"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2015.06.001"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/eru168"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-7909.2008.00708.x"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/plcell\/koab188"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-024-05316-w"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.12062"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.19.00480"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2018.00831"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.5511\/plantbiotechnology.10.0610a"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scienta.2009.01.008"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2019.110173"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.12723"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21031011"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.3390\/biology13050329"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41438-019-0233-4"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c03619"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2004.12.011"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.13647"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.8b01613"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0811684106"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43897-022-00023-2"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2008.02.015"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1080\/01140671.2017.1351378"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep12228"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-9452(02)00098-5"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00425-014-2152-9"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2021.712038"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1093\/hr\/uhac142"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.15877"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25042057"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2021.07.019"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2021.703994"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2016.01.014"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2014.12.001"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.14470"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-021-02977-9"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.13178"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2007.199"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1093\/hr\/uhac007"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1093\/hr\/uhac220"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.97"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21010247"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2015.00261"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo12090871"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes13112145"}],"container-title":["Plant, Cell &amp; Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pce.15398","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T01:48:27Z","timestamp":1749174507000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pce.15398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,20]]},"references-count":76,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/pce.15398"],"URL":"https:\/\/doi.org\/10.1111\/pce.15398","archive":["Portico"],"relation":{},"ISSN":["0140-7791","1365-3040"],"issn-type":[{"value":"0140-7791","type":"print"},{"value":"1365-3040","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,20]]},"assertion":[{"value":"2024-10-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}