{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T02:01:59Z","timestamp":1791597719613,"version":"4.3.4"},"reference-count":61,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Plant Cell &amp; Environment"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Plants activate induced defences through the recognition of molecular patterns. Like pathogen\u2010associated molecular patterns, herbivore\u2010associated molecular patterns (HAMPs) can be recognised by cell surface pattern recognition receptors, leading to defensive transcriptional changes in host plants. Herbivore\u2010induced defensive outputs are regulated by the circadian clock, but the underlying molecular mechanisms remain unknown. To investigate how the plant circadian clock regulates transcriptional reprogramming of a specific HAMP\u2010induced pathway, we characterised the daytime and nighttime transcriptional response to the caterpillar\u2010derived HAMP peptide In11 in the legume crop cowpea (\n                    <jats:italic>Vigna unguiculata<\/jats:italic>\n                    ). Using diel and free\u2010running conditions, we found that daytime In11 elicitation resulted in stronger late\u2010induced gene expression than nighttime. Plants with a conditional arrhythmic phenotype in constant light conditions lost time\u2010of\u2010day gated responses to In11 treatment, and this was associated with arrhythmic expression of circadian clock core transcription factor\n                    <jats:italic>Late Elongated Hypocotyl VuLHY1<\/jats:italic>\n                    and\n                    <jats:italic>VuLHY2<\/jats:italic>\n                    . Reporter assays with VuLHY homologues indicated that they interact with the promoter of daytime In11\u2010induced\n                    <jats:italic>Kunitz Trypsin Inhibitor<\/jats:italic>\n                    (\n                    <jats:italic>VuKTI<\/jats:italic>\n                    ) via a canonical and a polymorphic CCA1\/LHY binding site (CBS), consistent with a mechanism of direct regulation by circadian clock transcription factors. This study improves our understanding of the time\u2010dependent mechanisms that regulate herbivore\u2010induced gene expression.\n                  <\/jats:p>","DOI":"10.1111\/pce.70223","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T11:30:48Z","timestamp":1761219048000},"page":"4544-4557","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Circadian Clock Regulates Receptor\u2010Mediated Immune Responses to a Herbivore\u2010Associated Molecular Pattern"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3403-6661","authenticated-orcid":false,"given":"Natalia","family":"Guayaz\u00e1n Palacios","sequence":"first","affiliation":[{"name":"Department of Biology University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9396-4412","authenticated-orcid":false,"given":"Takato","family":"Imaizumi","sequence":"additional","affiliation":[{"name":"Department of Biology University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7493-678X","authenticated-orcid":false,"given":"Adam D.","family":"Steinbrenner","sequence":"additional","affiliation":[{"name":"Department of Biology University of Washington Seattle Washington 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