{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:54:25Z","timestamp":1791287665757,"version":"4.1.0"},"reference-count":52,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Plant Cell &amp; Environment"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Endophytic colonization by entomopathogenic fungi\n                    <jats:italic>Beauveria bassiana<\/jats:italic>\n                    enhances plant resistance to herbivores; however, the underlying molecular mechanisms, particularly those involving hormonal disruption of pests, remain poorly understood. This study examined whether root inoculation of tomato with\n                    <jats:italic>B. bassiana<\/jats:italic>\n                    suppresses whitefly\n                    <jats:italic>Bemisia tabaci<\/jats:italic>\n                    fitness via flavonoid modulation. Metabolomic profiling of leaf tissues showed a 3.5\u2010fold accumulation of the isoflavonoid genistein in\n                    <jats:italic>B. bassiana<\/jats:italic>\n                    \u2010inoculated plants. KEGG enrichment analysis indicated significant upregulation of the isoflavonoid biosynthesis pathway. Virus\u2010induced gene silencing of\n                    <jats:italic>SlHIDH<\/jats:italic>\n                    (2\u2010hydroxyisoflavanone dehydratase), a key gene in genistein biosynthesis, reversed the fungal\u2010mediated protection: it increased whitefly ovariole number by 20.5% and oviposition by 23.5% compared with the control. Correspondingly,\n                    <jats:italic>B. bassiana<\/jats:italic>\n                    inoculation downregulated seven whitefly reproduction\u2010related genes (\n                    <jats:italic>BtPLA<\/jats:italic>\n                    ,\n                    <jats:italic>BtJHAMT<\/jats:italic>\n                    ,\n                    <jats:italic>BtFPPS<\/jats:italic>\n                    ,\n                    <jats:italic>BtPER<\/jats:italic>\n                    ,\n                    <jats:italic>BtSPN<\/jats:italic>\n                    ,\n                    <jats:italic>BtELOVL<\/jats:italic>\n                    ,\n                    <jats:italic>BtAPN<\/jats:italic>\n                    ), whereas\n                    <jats:italic>SlHIDH<\/jats:italic>\n                    silencing abolished this effect and led to their upregulation. In artificial feeding assays, dietary genistein reduced oviposition by 32.9% and ovariole formation by 19.6%. Our findings demonstrate that\n                    <jats:italic>B. bassiana<\/jats:italic>\n                    elevates genistein levels in tomato, which impairs whitefly ovarian development and reproduction via endocrine disruption. These results reveal a tripartite interaction in which EPF enhances plant defense through specific secondary metabolites that target insect reproductive physiology, providing molecular insights for improving biocontrol strategies against sap\u2010sucking pests.\n                  <\/jats:p>","DOI":"10.1111\/pce.70504","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T03:26:21Z","timestamp":1775013981000},"page":"4926-4939","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Genistein Mediates\n                    <i>Beauveria bassiana<\/i>\n                    \u2010Induced Resistance Against\n                    <i>Bemisia tabaci<\/i>\n                    Reproduction in Tomato"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-2215-6028","authenticated-orcid":false,"given":"Qian","family":"Yuan","sequence":"first","affiliation":[{"name":"Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), College of Plant Protection Southwest University Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian","family":"Wang","sequence":"additional","affiliation":[{"name":"Engineering Research Center of Biotechnology for Active Substances (Ministry of Education) College of Life Sciences, Chongqing Normal University Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhou","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), College of Plant Protection Southwest University Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gan\u2010Wei","family":"Yan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), College of Plant Protection Southwest University Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao\u2010Lin","family":"Chen","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), College of Plant Protection Southwest University Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Jie","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), College of Plant Protection Southwest University Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Qiang","family":"He","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), College of Plant Protection Southwest University Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huai","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), College of Plant Protection Southwest University Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi\u2010Ying","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), College of Plant Protection Southwest University Chongqing 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